Exam Details
Subject | pharmaceutical chemistry –viii (medicinal chemistry - ii) | |
Paper | ||
Exam / Course | b.pharm | |
Department | ||
Organization | Gujarat Technological University | |
Position | ||
Exam Date | November, 2018 | |
City, State | gujarat, ahmedabad |
Question Paper
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code:260004 Date: 29/11/2018
Subject Name: Pharmaceutical Chemistry VIII (Medicinal Chemistry)
Time:02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Write a note on neuromuscular blocking agents with examples.
06
What are Cholinergics? What are their physiological actions? Give SAR of Acetylcholine.
05
What are CNS stimulants? Classify them. Give their uses and synthesis of Imipramine.
05
Q.2
Sketch the steps involved in synthesis of (any three): Salbutamol ii) Neostigmine iii) Ephedrine iv) Dopamine
06
What are opioid analgesics? How do they differ from NSAIDs?
05
Give main points of structure activity relationship of Morphine.
05
Q.3
Sketch the steps involved in synthesis of (any three): Procaine ii) Lignocaine iii) Benzocaine iv) Halothane
06
Write a note on factors affecting drug receptor interaction.
05
What is myasthenia gravis? Write the structures of the drugs used in the treatment of myasthenia gravis.
05
Q.4
Give the structure and IUPAC nomenclature of (any three): Amphetamine ii) Thiopental iii) Ibuprofen iv) Diclofenac
06
Write a note on antiparkinson drugs.
05
What is xenobiotics Explain Phase II reactions with examples.
05
Q.5
Classify the drugs used in epilepsy with examples. Which ring system is common to all of them? Sketch the steps involved in synthesis of Phenytoin.
06
What is schizophrenia? Explain SAR of Phenothiazine derivatives as CNS depressants.
05
Write a short note on psychomotor stimulants.
05
Q. 6
Write a note on stereochemical aspects of drug metabolism with examples.
06
Classify hypnotics and sedatives with examples. Give their uses and SAR of barbiturates.
05
Write a note on adrenergic antagonists.
05
Q.7
What are general anesthetics? How do they act? Give SAR of local anesthetics.
06
Write the advantages of selective COX-2 inhibitors over non-selective NSAIDs. Classify NSAIDs and write mechanism of action of Indomethacin.
05
Write a short note on narcotic antagonists.
05
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code:260004 Date: 29/11/2018
Subject Name: Pharmaceutical Chemistry VIII (Medicinal Chemistry)
Time:02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Write a note on neuromuscular blocking agents with examples.
06
What are Cholinergics? What are their physiological actions? Give SAR of Acetylcholine.
05
What are CNS stimulants? Classify them. Give their uses and synthesis of Imipramine.
05
Q.2
Sketch the steps involved in synthesis of (any three): Salbutamol ii) Neostigmine iii) Ephedrine iv) Dopamine
06
What are opioid analgesics? How do they differ from NSAIDs?
05
Give main points of structure activity relationship of Morphine.
05
Q.3
Sketch the steps involved in synthesis of (any three): Procaine ii) Lignocaine iii) Benzocaine iv) Halothane
06
Write a note on factors affecting drug receptor interaction.
05
What is myasthenia gravis? Write the structures of the drugs used in the treatment of myasthenia gravis.
05
Q.4
Give the structure and IUPAC nomenclature of (any three): Amphetamine ii) Thiopental iii) Ibuprofen iv) Diclofenac
06
Write a note on antiparkinson drugs.
05
What is xenobiotics Explain Phase II reactions with examples.
05
Q.5
Classify the drugs used in epilepsy with examples. Which ring system is common to all of them? Sketch the steps involved in synthesis of Phenytoin.
06
What is schizophrenia? Explain SAR of Phenothiazine derivatives as CNS depressants.
05
Write a short note on psychomotor stimulants.
05
Q. 6
Write a note on stereochemical aspects of drug metabolism with examples.
06
Classify hypnotics and sedatives with examples. Give their uses and SAR of barbiturates.
05
Write a note on adrenergic antagonists.
05
Q.7
What are general anesthetics? How do they act? Give SAR of local anesthetics.
06
Write the advantages of selective COX-2 inhibitors over non-selective NSAIDs. Classify NSAIDs and write mechanism of action of Indomethacin.
05
Write a short note on narcotic antagonists.
05
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- computer applications in drug discovery
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- cyber security
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- dispensing pharmacy ii and pharma industrial management
- dosage form design –i
- dosage form design- i
- dosage form design- ii
- dosage form design-i
- dosage form design-ii
- drug approval process
- environmental studies
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- food analysis
- forensic pharmacy
- forensic pharmacy-i
- genetic engineering and gene therapy
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- herbal cosmetics
- hospital and community pharmacy
- hospital management and medical tourism
- hospital pharmacy, community pharmacy & forensic pharmacy
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- human anatomy physiology
- human anatomy physiology and health education-ii
- human anatomy physiology-ii
- human anatomy, physiology and health education - i
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- instrumental and process validation
- intellectual property rights and patents
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- pharmaceutical analysis iii
- pharmaceutical analysis iv
- pharmaceutical analysis-i
- pharmaceutical analysis-ii
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- pharmaceutical chemistry –viii (medicinal chemistry - ii)
- pharmaceutical chemistry iii
- pharmaceutical chemistry iv
- pharmaceutical chemistry vii
- pharmaceutical chemistry-i
- pharmaceutical chemistry-i (inorganic chemistry)
- pharmaceutical chemistry-ii (physical chemistry)
- pharmaceutical chemistry-iii (biochemistry – i)
- pharmaceutical chemistry-iv (organic chemistry-i)
- pharmaceutical chemistry-ix (medicinal chemistry-iii)
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- pharmaceutical chemistry-v (biochemistry-ii)
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- pharmaceutical microbiology &biotechnology- ii
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- pharmacognosy iv
- pharmacognosy vi
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