Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: 260003 Date: 27/11/2018
Subject Name: Pharmaceutical Chemistry VII (Biochemistry)
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write a note on purine biosynthesis.
06

Write a note on β-oxidation of fatty acids along with its energetics.
05

Write a note on regulation of gene expression.
05
Q.2

Give urea cycle. Add a note on metabolic disorders of urea cycle.
06

Write a note on polymerase chain reactions.
05

Write a note on electrophoresis techniques used in biochemistry.
05
Q.3

Write a note on biosynthesis and utilization of ketone bodies.
06

Write a note on biosynthesis of RNA.
05

Give the importance of water and water metabolism in body.
05
Q.4

Write a note on catabolism of amino acids.
06

Write a note on respiratory chain.
05

Write a note on coenzymes involved in oxidation reduction reactions.
05
Q.5

Give the importance of iron and its metabolism in body.
06

Write a note on DNA repair mechanism.
05

Write a note on isolation and purification of nucleic acids.
05
Q. 6

Write a note on Sulphur containing amino acids. Also comment on disorders associated with them.
06

Write a note on formation and importance of bile pigments.
05

Write a note on metabolism of cholesterol.
05
Q.7

Write a note on oxidative phosphorylation. Also comment on its inhibitors.
06

Write a note on the specialized products formed from amino acids.
05

Enlist the enzymes involved in biosynthesis of porphyrin. Also add a note on porphyrias.
05