Exam Details

Subject medical science
Paper paper 1
Exam / Course civil services main optional
Department
Organization union public service commission
Position
Exam Date 2012
City, State central government,


Question Paper

Section ·A'
l. Describe the morphological features of full term placenta. Name any five congenital malformations of placenta.

12
Tabulate the extrinsic and intrinsic muscles of eyeball along with their nerve supply and action(s). 12
Define reflex. Classify them with examples and their significance in daily life. 12
Why pancreas is called a dual gland? What is the mechanism of hyperphagia in insulin deficiency How will you differentiate between hypoglycemic coma and hyperglycemic coma 12
Write a note on post translational modifications of protein. 12

2. Describe the shoulder joint under the following
headings: 6x5=30
Type of joint (Classification of joint)
Movements occurring at this joint
List main ligaments
Name the muscles acting at this joint (Do not describe each muscle)
Applied anatomy of dislocation of shoulder joint
What is meant by the term "frozen shoulder"

Describe the origin, course and function(s) of corticospinal tracts. Add a note on effect(s) of damage to these tracts and the resulting paralysis. 30

3. Discuss briefly the role of different hormones in lactation. Why there is amenorrhoea during lactation and what is its importance 5+10+5=20
List the various types of cells found in the blood and their functions. What will happen due to deficiency of each type 10=20
What are the effects of exercise on cardiovascular system What is the importance of exercise in maintaining the health of CVS 10+10=20
4. Describe the role of vitamins in prevention of
Anaemia. 20
Nodular growth in neck is very common among population living in mountain areas. Why How will you investigate such cases? 20
Write in brief about
Real time PCR
Hepcidin
VNTR
Tag Polymerase

Section
S. Define granuloma. Give the mechanism of formation of granuloma and give examples of granulomatous diseases. 12
Discuss cell-mediated immunity. 12

Explain why 3x4=12
Cloridine is not preferred as antihypertensive in patients of coronary heart disease.
Amiloride is a good choice as diuretic than thiazides in digitalised patient.
Prolonged therapy with ketoconazole produces endocrine adverse reactions.
Racemic mixture of dobutamine is used to treat acute congestive heart failure.

How will you solve the problem of interchange of newborn babies in a Hospital 12
Give the incidence, pathogenesis gross and microscopic features of Rheumatic heart disease. 12

6. Give the etiopathogenesis and gross and microscopic features of acute osteomyelitis. 20
Give the FAB classification of acute myeloid leukaemia and discuss the laboratory findings in a case of M3 AML. 20
Discuss laboratory diagnosis of AIDS.
10
Discuss pathogenesis and laboratory diagnosis of extraintestinal amoebiasis. 10

7. Discuss pathogenesis and laboratory diagnosis of cryptococcosis. 20
Classify immunosuppressive drugs. Describe in brief the mechanism of action and side effects of cyclosporine. Mention the advantage of serolimus as immunosuppressant. 20
How will you differentiate between benign and malignant tumours 20

8. Describe the structure of a catridge of a smooth barrel shotgun and its mechanism of fire. 20
Describe the signs, symptoms and management of chronic lead poisoning. 20
How will you establish on medical examination and examination of trace evidences that alleged virgin woman of 15 years was sexually assaulted by an adult male 20


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