Medical Sciences: IAS Mains: 2001
Paper-I
Section A

Answer any three of the following in not more than 200 words each:

Describe the gross and microscopic anatomy of lung. Add a note on developmental anomalies of lung

Describe the structure and functions of ovary

Describe the role of hypothalamus in the control of secretion of pituitary hormones. How is body temperature regulated by the hypothalamus

What is Michaelis constant? How is the difference in this constant between hexokinase and glucokinase important in the utilization and regulation of blood glucose levels? What would have been the consequences if normal distribution of hexokinase and glucokinase in liver and muscles were reversed

Answer the following questions

Describe pelvic disphragm. Add a note on supports of uterus

Describe optic pathways and write a note on development of eyeball

Write a short note on genotype and phenotype of Turner's syndrome

Answer the following questions

Compare with the help of a diagram the length-tension relationship for skeletal, cardiac and smooth muslces. What is the latch phenomenon in smooth muscle

Describe the reflex arcs of stretch and inverse stretch reflexes. What are the differences in the properties of monosynaptic and polysynaptic reflexes

How are platelets formed? Describe the properties and functions of platelets

Answer the following questions

Write a transamination reaction. How is this reaction important in amino acid metabolism? Which vitamin is required in this reaction

Give a flow chart to depict synthesis of mRNA in eucaryote. State the post-transcriptional modifications

With the help of a diagram depict the metabolic interlinks between chylomicron, VLDL and LDL

Section B

Answer any three of the following in not more than 200 words each:

Write differences between beneign and malignant tumours and describe the pathways of spread of cancer

Discuss briefly basic procedure and clinical applications of polymerase chain reaction

Describe drug receptor interaction and uses of partial agonists in therapeutics

What is the medico-legal importance of “Diatom”

Answer the following questions

Discuss etiopathogenesis and pathology of peptic ulcer

Discuss pathogenicity and laboratory diagnosis of Herpes simplex virus infection

Write briefly about the following:

Tuberculous meningitis

Candidiasis (10 10 20)

Answer the following questions

Describe indications, contraindications and adverse effects of ACE inhibitions

Write indications, contraindications and adverse effects of metronidazole

Give mechanism of action, therapeutic uses of chloroquine

Answer the following questions

Classify various types of injuries. How will you estimate age of “Bruise”

Enumerate insecticides used in agriculture. Describe toxic effects of organophosphorus poison in human beings

Write a note on Exhumation