+Medical Sciences: IAS Mains: 2000
Paper-I

Answer any five of the following questions in not more than 200 words each:

Describe the microscopic anatomy of testis. Add a note on spermatogenesis

Describe structure and functions of placenta at term

What is plantar reflex? How it is elicited? Describe ifs nerve supply and importance

What is nerve-supply of carotid sinus? What are the functions of carotid sinus

Enumerate with suitable examples the mechanisms involved in conversion of a substrate to its products through an enzymatic reaction

Schematically depict the integration of the metabolic activities in liver and muscle in regulation of blood glucose after 72 hours of starvation

Section A

(Anatomy, Physiology Biochemistry)

Answer the following questions

Describe the formation of inguinal canal. Add a note on inguinal hernias

Describe the course and distribution of mandibular branch of fifth cranial nerve

Answer the following questions

What is the mechanism, sites of actions and of origin of insulin? What other hormones balance it in human body and how

What are the main factors which maintain and regulate venous return

What are the factors which increase oxygen supply to more active tissues

Answer the following questions

Sequence the events contributing to the regulation of plasma cholesterol levels as a consequence of receptor mediated uptake of LDL by hepatic and extra-hepatic tissues

What is ketoacidosis? How will you differentiate between metabolic acidosis and respiratory acidosis

Section B

(Pathology, Microbiology, Forensic Medicine, Pharmacology and Toxicology)

Answer any five of the following questions in about 200 words each:

Explain the terms metaplasia, anaplasia, dysplasia, hyperplasia and hypoplasia with suitable examples

What are the complications and sequelae of streptococ-cal sore throat? Discuss its treatment

Discuss the role of biologic agents in the etiopathogenesis of neopiasia

Give indications, contraindications and side effects of rifampin

Discuss the mechanism of action, therapeutic uses and adverse effects of methotrexate

How will you use the blood grouping system in case of disputed paternity

Section C

(Pharmacology Forensic Medicine Toxicology)

Answer the following questions

Define cirrhosis of liver. Classify cirrhotic conditions of liver. Discuss the etiopathogenesis and pathology of primary biliary cirrhosis

Discuss the etiopathogenesis and pathological lesions of rheumatic fever

Answer the following questions

How will you determine whether the incised wound is ante mortem or post mortem

Enumerate various physical and chemical tests to confirm the presence of semen in a given sample

Discuss the various methods for control of rabies in India

Answer the following questions

Classify non-narcotic analgesics

Discuss the mechanism of action, dosage and toxicity of doxycycline

Describe the mechanism of action, dosage and adverse reactions of dapsone