Medical Sciences: IAS Mains: 2006
Paper-I
Section A

Attempt any three of the following: × 20 60)

Describe the development of FACE with the help of a diagram. Mention the anomalies associated with it.

Describe the gross anatomy of caecum and vermiform appendix. Add a brief note on its applied anatomy.

List the features of cerebellar lesions and their physiological basis.

The protein molecular ultimately needed by a cell often differs from the polypeptide chain synthesised. How is the chain modified to impart biological activity? Describe with suitable examples.

Answer the following questions

Give an account of blood supply of heart. Add a brief note on its applied anatomy

What is accommodation of eye? How is the eye accommodated for near vision? Why does a person start having difficulty in reading after the age of 40 years though the visual acuity is 6/6

Describe the lymphatic drainage of Mammary Gland (Breast). Give an account of its applied anatomy

Answer the following questions

Name the hormones of posterior pituitary and their function. What will happen in the deficiency of them

Describe normal menstruation. Why is it absent during the first few months of lactation

What will be the consequences if a Rh-ve mother carries a Rh ve fetus and how can they be prevented

Answer the following questions

Enumerate with suitable examples vitamin coenzymes involved in oxidation-reduction reactions. Describe at least three vitamers

Define sinus arrythmia. How is it produced and what is its clinical significance

Non-essential amino acid tyrosine is formed from phenylalanine. How does the conversion take place and how is tyrosine utilised for the formation of hormones

Section B

Answer any three of the following: × 20 60)

What is carcinogenesis? Classify carcinogens. Write in short about important carcinogens.

Name various methods of acquisition of new genes in bacteria. Discuss in detail mechanism of drug resistance in bacteria.

Describe drug-receptor interactions. Discuss G-protein coupled receptor mediated actions of drugs with suitable examples.

How will you determine the rarjge of a firearm in case of fire from a shotgun?

Answer the following questions

Describe aetiopathogcnesis of glomerulonephritis in brief. Describe different types of glomerulonephritis in short

Discuss virus-host cell interactions and immunity in infection caused by viruses

Name various parasites causing anaemia. Discuss morphology, life cycle, pathogenicity and laboratory diagnosis of Ancylostonm duodende

Answer the following questions

Give examples of non-steroidal anti-inflammatory agents. Mention the advantages and adverse effects of selective COX-2 inhibitors as anti-inflammatory agents

Discuss the therapeutic applications of immunosuppressive therapy. Compare the actions of cyclosporine with glucocorticoids as immunosuppressive drug

Discuss the mechanism of action and therapeutic uses of calcium channel blockers. Mention the advantages of dihydropyridines in the treatment of angina pectoris

Answer the following questions

How do you determine the-extent of burn? What is the difference between ante-mortem and postmortem burns

How can you differentiate between hanging and strangulation? Discuss in detail

Discuss in detail various examinations done in the laboratory to identify a blood stain