FACULTY OF PHARMACY
B. Pharmacy 3/4 II Semester (Main) Examination, April 2018
Subject: Physical Pharmacy II
Time: 3 Hours Max.Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Write various solubility expressions as per IP. 3
ii) Explain solvent solute interaction with examples. 11
OR
Define ideal and real solutions. 3
ii) Explain solubility of solids in liquids. 11
2 Define the terms: Rate constants, Half life and shelf life. 4
ii) Explain the principle and procedure involved in accelerated stability testing. 10
OR
Define: Rates, order, and molecularity of reactions. 4
ii) Discuss the influence of temperature and solvents on reaction velocity. 10
3 Give the classification of interfaces. 3
ii) Explain the solid-gas interface and elaborate on adsorption isotherm. 11
OR
Write the applications of surfactants. 4
ii) Elaborate on electric properties of interfaces. 10
4 Explain porosity, various powder densities and their importance in formulation. 4
Write about particle size, size distribution by sieve method. 10
OR
Compare the properties of Lyophilic and Lyophobic solutions. 4
Explain the kinetic and electric properties of colloids. 10
5 What is Rheology? Explain Newtonian and Non-Newtonian flow systems with the
help of Rheograms. 7
What is thixotropy? Explain with the help of Rheograms. Write the applications of
thixotropy. 7
OR
What are polymers? Write the applications of polymers as thickening agents. 7
Describe the method of determining the viscosity with cup or cone viscometer. 8