Master of Science I (Microbiology) Examination: Oct Nov 2016
Semester I (Old CBCS)
SLR No. Day
Date Time Subject Name Paper
No. Seat No.
SLR SO
616
Monday
21/11/2016
10.30 AM
to
01.00 PM
Recent Trends in Virology
C
III
Instructions

Part I is compulsory.
Attempt any four questions from Part II.
Part I and Part II should be written in same answer book.
Figures to the right indicate full marks.
Total Marks: 70
PART I
Q.1 Rewrite the following sentences by selecting correct answers from given
alternative.
14
Polystyrene latex is used for enumeration of viruses in sample by

Pock method Direct microscopic count
Acid end point method Hemagglutation assay
Human body produces as antiviral substance.
Antibody Antigen
Interferon Immunogen
LHT system of viral classification grouped DNA viruses into class.
Retroviruses Retroviridae
Ribovira Deoxyvira
is temperate phage.
λ T4
T3 θ X174
Yolk sac is useful for cultivation of virus.
TMV Rabies
Herpes simplex Plant
In lambda phage gene is responsible for the lysogenic state.
Q A
R C1
One step Growth Experiment was devised by
Watson Crick
Lederberg Delbruck
Lipid bilayer membrane of poxviruses is originated from host cell.
Plasma membrane Nuclear membrane
Endoplasmic Reticulum Golgi Apparatus
Page 1 of 2
Viroids were discovered by
Diener Puschner
Boin Baltimore
10) The name of Order in ICTV system always ends with suffix
VIridae Virales
Vira Viraceae
11) Rabies virus is shaped.
Icosahedral Helical
Spherical Bullet
12) lacks protective capsid around the nucleic acids.
Slow viruses Viroids
Prions Naked Viruses
13) can undergo antigenic shift.
Rabies Hepatitis
Influenza Pox
14) Hubner and Todaro proposed theory.
Provirus Proto virus
Oncogene Somatic mutation
PART II
Q.2 Describe in detail Cultivation of viruses using embryonated eggs and cell
cultures.
14
Q.3 Discuss in detail Control of viral infections with vaccines and chemotherapeutic
agents.
14
Q.4 Write short answers any two: 14
Describe briefly reproduction of DNA and RNA bacteriophages.
Discuss briefly Host cell transformation by viruses.
Describe briefly multiplication of Adeno viruses.
Q.5 Write short answers any two: 14
Describe briefly emerging viral infections.
Discuss briefly Assay of infectivity.
Draw labeled diagram of the influenza virus and add a note on antigenic shift
and antigenic drift.
Q.6 Write short answers any two: 14
Satellite viruses
Discovery of viruses
ICTV