M.Sc. (Semester (CBCS) Examination Mar/Apr-2018
Microbiology
RECENT TRENDS IN VIROLOGY
Time: 2½ Hours
Max. Marks: 70
Instructions: Part questions 1 is compulsory. Attempt any four questions from Part II.
Figures to the right indicate full marks. Answer to the Part I and Part II should be written in same answer booklet only.
Part I
Q.1
Rewrite the sentences by choosing correct given below:
14
A structural component that is found in all viruses is
The envelope
DNA
Capsid
Tail fibers
A type of cell culture that can reproduce for an extended number of generations and is used to support viral replication is a
Primary cell culture
Continuous cell line
Cell strain
Diploid fibroblast cell
is not a RNA virus?
Retrovirus
Enterovirus
Rhabadovirus
Adenovirus
Bacteriophage are readily counted by the process of
Immunoassays
ELISA
Plaque assays
Tissue cell culture
Viruses range in size from
1-100 nm
25-300 nm
10-100
400-1000 nm
Potato spindle tuber disease is caused by
Virus
Prions
Exons
Viroids
Elution process is observed in virus.
Influenza
Picorna virus
Mumps
Rubella
A common polyhedral capsid shape of viruses is a
Pentagon
Cube
Icosahedrons
Pyramid
Viruses that can remain latent (usually in neurons) for many years are most likely
Toga viruses
Herpes viruses
Entero viruses
Rhinoviruses
Page 2 of 2
SLR-UQ-532
10) Types of viruses contain the enzyme lysozyme to aid in their infection.
Bacteriophage
Animal Viruses
Plant Viruses
Fungal Viruses
11) The phage ØX-174 genome penetrates the host cell with help of pilot protein which is product of
K gene
A gene
J gene
H gene
12) For safety reasons, is the least likely vaccine against HIV?
Purified Gag/Pol Polyprotein
Purified Gag Polyprotien
Attenuated virus
The virus' capsid proteins
13) Common recurrent disease produced by herpes virus type 1 is
Neonatal Encephalitis
Cold sores
Eczema herpeticum
Genital warts
14) Antiviral substance produced in human body is
Interferon
Antigen
Antibody
Immunogen
Part II
Q.2
Write in detail on structure, genomic organization, pathogenesis and control of HIV virus.
14
Q.3
Explain in detail the characteristics of transformed cells and comments on how these cells are responsible for tumor development?
14
Q.4
Write short answer on any two of the following:
14
Briefly describe Prions.
Briefly describe Emerging viruses with example.
Describe in detail production of Ø X-174 bacteriophage.
Q.5
Write short answers Any Two:
14
Describe in detail satellite viruses.
Explain in detail multiplication, pathogenesis and control of plant viruses.
Briefly describe Cataloging of the viruses.
Q.6
Write short answers Any Two:
14
Describe in detail Viroids.
Explain in brief Viruses pathogenic to algae and fungi.
Briefly describe classification and nomenclature of animal viruses.