Master of Science I (Microbiology) Examination: Oct Nov 2016
Semester I (New CBCS)
SLR No. Day
Date Time Subject Name Paper
No. Seat No.
SLR SO
611
Monday
21/11/2016
10.30 AM
to
01.00 PM
Recent Trends in Virology
HCT 1.3
Instructions

Q.1, Part I is compulsory.
Attempt any four questions from Part II.
Part I and Part II should be written in same answer book.
Total Marks: 70
PART I
Q.1 Rewrite the following sentences by selecting correct answers from given
alternative.
14
are the only viruses that produce genome DNA by reverse
transcription with mRNA as the template.
Hepadnaviruses Retroviruses
Influenza viruses SARS viruses
is defective virus?
Influenza SARS
Marburg Hepatitis D
is also known as enterovirus 71?
Hepatitis A Hepatitis E
Polio Rota
For safety reasons, is the least likely vaccine against HIV?
Purified Pol polyprotein Purified Gag polyprotein
Attenuated virus The capsid proteins
NPV means which causes infection to insect.
Nuclear polyhedrosis virus Neutral prasatic virus
Nonpermsive virus All of these
Attenuate virus vaccines is too dangerous for some viral diseases because

Attenuated vaccines would induce only humoral immunity in the patient
receiving them.
Because the virus is attenuated, the patient's immune system would not
generate an immune respone against it.
The attenuated virus might mutate as it is replicating in the patient and
revert back to its virulent form.
An attenuated vaccine may not generate protective immunity because only
a portion of the viral genome is used.
In Hepatitis C virus is genome.
RNA ssDNA
ds DNA Semented RNA
Common recurrent disease produced by Herpes virus type 1 is

neonatal cold sores
eczema herpeticum genital Encephalitis
Page 1 of 2
If an adult patient has fever, sore throat, and lymphadenopathy accompanied
by lymphocytosis with atypical cells the diagnosis most likely is

measles infectious mononucleosis
infectious hepatitis viral meningitis
10) Generally the incubation period of influenza is
1 to 2 days 10 to 15 days
14 to 20 days 20 to 30 days
11) The measles virus
elutes spontaneously from agglutinated cells
has many antigenic types
is highly contagious for only humans
contains neuraminidase molecules
12) Concerning the pathogenesis of influenza
the virus enters the host in airborne droplets
pneumonia is not always associated with secondary bacterial invaders
necrosis of the upper respiratory tract is common
viremia is not present in the nasopharynx before the onset of the
symptoms
13) Which of the following describe cytomegalovirus?
It is a member of the herpes viruses
It is known to be the most common cause of congenital viral infection
transmission from mother to child can be in-utero, perinatally or through
breast feeding
All of above
14) SARS disease means
Severe acute respiratory syndrome
Severe acquired respiratory syndrome
Severe associated respiratory syndrome
Slowly acquired respiratory syndrome
PART II
Q.2 Write in detail on structure, genomic organization, pathogenesis and control of
orthomyxovirus virus.
14
Q.3 Explain in detail multiplication, pathogenesis and control of plant viruses. 14
Q.4 Write short answers (any 14
Describe in detail structure, genomic organization and reproduction of
phage
Briefly describe bacteriophages.
Prions
Q.5 Write short answers (any 14
Draw labeled diagram of the HIV and add a note on its pathogenesis and
control.
Briefly describe Cataloging of the viruses.
Describe in detail morphogenetic pathway for production of T4bacteriophage.
Q.6 Write short answers (any 14
Describe in detail virioids
Briefly describe Emerging viruses with example.
Describe in detail viral assay with reference to infectivity assay.