M.Sc. (Semester (CBCS) Examination Oct/Nov-2017
Microbiology
RECENT TRENDS IN VIROLOGY
Day Date: Tuesday, 21-11-2017 Max. Marks: 70
Time: 10.30 AM to 01.00 PM
Instructions: Part questions 1 is compulsory.
Attempt any four questions from Part II.
Figures to the right indicate full marks.
Answer to the Part I and Part II should be written in same answer booklet
only.
Part I
Q.1 Rewrite the sentences by choosing correct given below: 14
Antigenic variation is most extensive in
Mumps influenza
herpes measles
The phage ØX174
genome penetrates the host cell with the help of pilot
protein which is product of
H gene A gene
J gene K gene
In the reproductive cycle the gene N product acts as
Repressor Anti repressor
Anti terminator Terminator
a DNA containing Oncogenic virus.
Rous Sarcoma virus Leukemia virus
Epstein-Barr virus Mammary tumor virus
Hemagglutination assay is suitable for enumeration viruses.
Nacked Enveloped
Complex All
Terminal protein of 55 k is attached to the end of the DNA of
Influenza Pox
Polio Adeno
The incubation period of viral hepatitis type A is
360 to 900 days 15 to 45 days
5 to 10 days 3 to 5 days
Which of the following properties describes the nature of viruses?
They multiply inside and outside cells.
They are parasites at the genetic level.
They are not dependent on the host cells' protein synthesizing apparatus
They are not dependent of the host cells' energy-yielding apparatus
the TMV first time.
Hershey Chase
Stanley Sanger
Page 2 of 2
SLR-MQ-581
10) E.coli K-12 is host bacteriophage.
T4 T1
T3
11) The ability of an animal virus to infect a cell depends primarily
Whether or not the host cell has a nucleus.
The enzymatic activity of the host cell.
The types of viral nucleic acid.
Presence of receptor sites on the cell membranes.
12) the BEST description of all types of viruses that have an RNA
genome.
They always contain a gene encoding RNA- dependent RNA or DNA
polymerase and have higher mutation frequencies relative to viruses
containing DNA genomes.
The viral genomes can always act as mRNA.
The virions of RNA viruses always contain an RNA-dependent RNA or
DNA polymerase protein.
They are always single stranded.
13) In Pock assay, viral dilution is inoculated onto the surface of
Allantoic cavity Amniotic cavity
Yolk sac Chorioallantoic membrane.
14) The term viroid was discovered
Diener Puschner
Boin Baltimore
PART II
Q.2 Write in detail on structure, genomic organization, pathogenesis and control of
Picorna virus.
14
Q.3 Discuss in detail the characteristics of transformed cells by cancer producing
viruses.
14
Q.4 Write short answer on any two of the following: 14
Describe in detail ultra structure, morphology of viruses.
Describe in detail cultivation of animal viruses.
What are interferons? Describe their mode of action and its clinical use.
Q.5 Write short answers Any Two: 14
Draw labeled diagram of the TMV and add a note on its pathogenesis and
control.
Briefly describe emerging viral infections.
Describe in detail satellite viruses.
Q.6 Write short answers Any Two: 14
Briefly describe phage.
Briefly describe classification and nomenclature of animal viruses.
Describe in detail assay of viruses.