FACULTY OF PHARMACY
B. Pharmacy 4/4 II-Semester (Main) Examination, April 2017
Subject Pharmacoinformatics
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Write briefly about Data mining and KDD.
Describe briefly about database architecture
OR
What are biological databases? Classify and write the importance of biological
databases.
Write about Chemi informatics databases.
2 What is Hidden Markov model? Describe briefly about its construction and use in
alignment and prediction.
What is sequence alignment? Write dynamic programming method for sequence
alignment.
OR
Explain briefly about:
Search machines Homology searches
Pattern matching Bio-Perl
3 Describe in detail about the Drug information resources.
Write a short note on preparation of written and verbal reports.
OR
Write about coding of information and bar-codes.
Explain pharmacy automation applications in medication dosage, distribution,
management and inventory control.
4 What are DNA sequencing methods? Write about conventional and automated DNA
sequencing.
Write short notes on libraries.
OR
What are the biological databases? Explain the following databases.
Genbank Prosite SCOP CATH
5 What is SAR and QSAR? Explain QSAR methods for drug design.
Write a brief note on molecular docking.
OR
Write and explain the theories for drug-receptor interactions.
Write a brief note on Quantum mechanics Energy minimization