FACULTY OF PHARMACY
B. Pharmacy 4/4 II-Semester (Main) Examination, April 2016
Subject: Pharmacoinformatics
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks
1 What is the concept of database and classify them?
Write about data mining and Knowledge Discovery in Databases
OR
Write about codd's rules in databases.
Write about normalization in database.
2 What is sequence alignment? Write about dynamic programming method for
sequence alignment?
OR
Write about Hidden Markov model and its applications in alignment and prediction?
Write about Homology search and pattern matching.
3 Describe in detail about the drug information services and resources available.
Write about bar-coding in pharmacy.
OR
What is pharmacy automation? Write about automated medication dosage, filing
and packaging.
4 Describe about homology search algorithms for proteins and nucleic acids. (BLAST
and FASTA)
OR
What are biological databases? Give their importance and write about databases
for protein structure. SCOP and CATH).
5 What is QSAR Write about QSAR methods and applications of QSAR (Hansch
Analysis and Free-Wilson Analysis).
OR
What are the theories for drug receptor interactions? Explain them.