FACULTY OF PHARMACY
B. Pharmacy IV Year II Semester (Main) Examination, March April 2016
Subject: Pharmacoinformatics
Time: 3Hours Max.Marks: 70
Note: Answer all questions. All questions carry equal marks.
What is database? Write about sequence and structural databases.
Discuss about drug information databases.
OR
Write about codd's rules in databases.
Describe briefly about database normalization and database architecture.
What is Hidden Markov model? Describe briefly about its construction and use in
alignment and prediction.
OR
What is an algorithm? What are the algorithms used in sequence alignment for
proteins and nucleotides?
Describe in detail about the drug information services and resources available.
OR
What is pharmacy automation? Write about automated medication dosage, filling
and packaging.
What are biological databases? Write the databases useful for proteins and
nucleic acids.
OR
Write about BLAST and FASTA for homology searches of proteins and nucleic
acids.
What is QSAR? Write about QSAR methods and applications of QSAR.
OR
What is energy minimization? Write the importance of energy minimization in
drug design.
Write briefly about factors affecting the bioactivity of drugs.