FACULTY OF PHARMACY
B. Pharmacy 4/4 II-Semester (Makeup) Examination, September 2017
Subject Pharmacoinformatics
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 What is Database? Classify and write about different types of databases.
What are relational databases? Write about Codd's rules.
OR
Write about Bibliographic databases and Library Catalogs.
Write about Phylogenetic analysis.
2 What is sequence alignment? Explain Needleman-Wunsch algorithm for
sequence alignment.
Write a brief note on substitution similarity matrices.
OR
Write about storage and retrieval of information from databases.
Write a short note on Homology search Pattern matching
3 Discuss about drug information resources with merits and demerits.
Write a note on about emergency treatment of poisoning.
OR
What is Pharmacy Automation? Write its application in medication dosage,
filing and packaging, medication distribution and inventory control.
4 Write about DNA databanks.
Explain BLAST algorithms for proteins and nucleic acids.
OR
Write a note on
Cosmid libraries SWISSPROT SCOP EMBOSS
5 What is SAR and QSAR Explain Hansch analysis and Free-Wilson analysis for
drug design.
Write about energy minimization.
OR
Explain theories of drug receptor interactions.
Explain Molecular Docking Bioisosterism