FACULTY OF PHARMACY
B. Pharmacy 2/4 I-Semester (Main) Examination, November 2016
Subject Pharmaceutical Analysis I (Chemical Analysis)
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Define the terms accuracy and precision. Explain the difference between
them with suitable examples.
Describe different methods of expressing concentration of solutions.
OR
Discuss about the statistical treatment of analytical data. Write notes on
rejection of doubtful value.
Define the following terms and give examples with required properties
Primary standard Secondary standard
2 Define the terms buffer, buffer action and buffer capacity. Discuss the role of
buffers in pharmaceutical analysis.
Write Arhenious theory of acids and bases.
OR
Explain the terms acidimetry and alkalimetry with suitable examples.
Discuss the theories of neutralization indicators.
3 Discuss the principles involved in gravimetry. Explain about co-precipitation
and post precipitation with suitable examples.
How do you prepare and standardize 0.1 K2Cr2O7.
OR
Explain Iodimetry and Iodometry with suitable examples. Discuss the use of
starch as indicator in redox titration and its limitations.
Write a note on drying procedures followed in gravimentry.
4 Discuss the principle involved in complexometric titration. Write short notes
on PM indicators.
Write the principle and procedure involved in estimation of magnesium
sulphate.
OR
Write brief account on principles of gas analysis.
Discuss about the solvents and indicators used in non-aqueous titration.
5 Define the terms:
Normality Molarity
Theoretical yield Percentage yield
Write the mass balance equation for the following:
KBr KBrO3 KCl Br2 H2O
CaCO3 HCl CaCl2 H2O CO2
OR
What is avagadro's number? Write an account on determining moles of
elements in compounds.
Find the pH of a solution in which 4.0 x 10-5 mol /dm3