FACULTY OF PHARMACY
Pharm D. YDC) III Year (Main) Examination, September 2017
Subject Pharmaceutical Analysis
Time 3 hours Max. Marks 70
Note: Answer all questions from Part-A. Answer any FIVE questions from Part-B.
PART A (10 x 2 20 Marks)
1. Write the different factors effecting fluorescence phenomenon. 2
2. Explain different types of peaks in mass spectrum. 2
3. Give pharmaceutical applications on DSC technique. 2
4. State and explain Beer-Lamberts law. 2
5. Write the principle involved in conductometric titration of strong acid Vs strong
base. 2
6. Write about sampling of solids in IR spectroscopy. 2
7. Give advantages and disadvantages of Hydrogen Electrode. 2
8. Explain about different derivatization techniques in gas chromatography. 2
9. Define retardation factor and how do you calculate. 2
10.Define validation and give the importance of validation of analytical methods. 2
PART B x 10 50 Marks)
11. Describe the calibration procedure of UV-visible spectrophotometers. 10
12. Write about different types of detectors used in HPLC chromatograph. 10
13. Discuss the principles and applications of flame photometry technique. 10
14.a) Write about different types of vibrations in IR spectroscopy. 5
Give applications of fluorimetry. 5
15.a) Give description and working of DME. 5
Write its advantages and disadvantages. 5
16.a) Write the principles and applications of DTA. 5
Make a note on X-ray diffraction patterns. 5
17.a) Explain different methods for measurement of potential and pH. 5
List out different types of Indicator and reference electrodes used in
potentiometric titrations. 5
18. Discuss the principles and theory involved in NMR and ESR techniques. 10