FACULTY OF PHARMACY
Pharm D. YDC) III Year (Instant) Examination, January 2018
Subject Pharmaceutical Analysis
Time 3 hours Max. Marks 70
Note: Answer all questions from Part-A. Answer any FIVE questions from
Part-B.
PART A (10 x 2 20 Marks)
1 Explain fluorescence and phosphorescence phenomena. 2
2 Give different types of fuel gases and oxidants used in flame photometry
technique. 2
3 Explain Beer-Lambert's law. 2
4 Define chemical shift and give different scales for its measurement. 2
5 Explain Bathochromic and Hypsochromic shifts with examples. 2
6 Write Ilkovic's equation and explain. 2
7 Give advantages of amperometric titrations over potentiometry. 2
8 Explain current-voltage curve in polarography. 2
9 Give Nernst equation for calculation of Electrode potentials. 2
10 Write differences between HPLC and HPTLC techniques. 2
PART B x 10 50 Marks)
11 Write ICH guidelines for validation of HPLC methods 10
12 Describe the instrumentation and working of IR-spectrophotometer with a neat
sketch. 10
13 Discuss the principles of separation by electrophoresis and give details of gel
electrophoresis. 10
14 Describe the different components of a differential scanning calorimeter 10
15 Discuss the principle and theory involved in NMR and ESR techniques 10
16 Explain in detail about the detectors used in gas chromatography. 10
17 Explain optical Rotary dispersion and circular dichroism. 5
Write the principles of Mass spectroscopy and about different types of peaks
in mass spectrum 5
18 Write about single component methods for analysis of medicinal substances by
UV-visible spectrophotometry. 10