FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER IV
PATH/J/16/32/IV
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Transfusion transmitted infections in thalassemics.
Cord blood banking.
5+5
2. Immunomodulatory therapy in associated
lymphoproliferative disorders.
Red cell membrane defects.
5+5
3. Interplay between haemostatic pathway and cancer
biology.
Gene expression profiling in lymphomas.
5+5
4. Diagnosis of autoimmune haemolytic anaemia.
pANCA.
5+5
5. Platelet disorders and their investigation.
Role of flow cytometry in leukemia diagnosis.
5+5
6. Differential diagnosis of chronic lymphoproliferative
disorders.
Recurrent chromosomal changes in AML.
5+5
7. Lab diagnosis of hemolytic uremic syndrome (HUS).
Pathogenesis of multiple myeloma.
5+5
8. Parvo virus infection and its haematological changes.
Blood components and their preparation in blood bank.
5+5
9. Prostaglandins and their role in thrombus formation.
Name various red cell indices measured by automated
hematology analysers and their role in evaluation of
anemia.
5+5
10. Agranulocytosis.
Fibrin degradation products.
5+5