FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2017
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER IV
PATH/J/17/32/IV
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Revised WHO 2016 Classification for chronic
myeloproliferative disorders.
Iron resistant iron deficiency anemia.
5+5
2. Minimal residual disease in acute leukemia.
Laboratory approach for diagnosis of thrombophilia.
5+5
3. Secondary autoimmune hemolytic anemia.
Molecular and genetic pathobiology of multiple myeloma.
5+5
4. Transfusion related acute lung injury.
JAK 2 mutations in hematological malignancies.
5+5
5. Hematological changes in dengue fever.
Principles of automated blood cell counters.
5+5
6. Algorithm to use of blood component therapy in bleeding
disorders.
Approach to diagnosis of hemoglobinopathies.
5+5
7. Laboratory diagnosis of acquired inhibitors of coagulation.
Principles and uses of HPLC.
5+5
8. Bone marrow failure syndrome.
Role of bone marrow biopsy in diagnosis and staging of
lymphomas.
5+5
9. Biochemical basis of megaloblastic anemia.
Medicolegal liabilities in laboratory medicine.
5+5
10. Peripheral blood stem cell transplantation.
Hematological manifestations of HIV infection.
5+5