FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
APRIL 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER IV
PATHO/APRIL/16/32/IV
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Define and classify hemophagocytic syndrome, and
approach to its lab diagnosis.
Waldenstrom microglobulinemia.
6+4
2. Hematological changes in dengue fever.
Etiology and diagnosis of Pure Red Cell Aplasia.
5+5
3. Infectious complications of blood transfusion.
Value of reticulocyte preparation in diagnosis of anemia.
5+5
4. Morphology of primary myelofibrosis.
Hypoplastic acute leukemia.
5+5
5. Pathophysiology of sickling
Molecular basis of mixed lineage leukemia.
5+5
6. Lab diagnosis of macrocytic anaemias.
Pathogenesis and lab diagnosis of hypereosinophilic
syndrome.
5+5
7. Antiphospholipid syndrome.
Hematological manifestations in HIV disease.
5+5
8. Diagnostic criteria of multiple myeloma.
Hematological manifestations of SLE.
6+4
9. Secondary polycythemia.
Prognostic markers of acute lymphoblastic leukemia.
5+5
10. Prolymphocytic leukemia and its differential diagnosis.
International Normalized Ratio its derivation and
significance.
6+4