1. Tesla is the unit of:

Magnetic flux density

Resonance

Photon flux

Mass charge


2. If two linear single stranded DNA molecules are heated to 368 K followed by cooling to
278 the product formed is

Double stranded DNA with blunt ends

Double stranded DNA with overhangs

Single stranded circular DNA

Linear single straded DNA


3. A fires 7 shots to but A kills only once in 4 shots while B kills once in 2 shots. When B has missed 20 times, A has killed:

90 birds

14 birds

25 birds

20 birds

4. The calculated bond order in O2-ion is

1.0

1.5

2

2.5

5. Protein A and B have similar migration on native page; while Protein A shows two times
higher molecular weight than protein B on SDS PAGE, which of the following is true:

A and B are monomeric

A and Bare dimeric

A is monomeric and B is dimeric

A is dimeric and B is monomeric


6. LED -television works on the following principle

Luminescence

Phosphorescence

Electro Luminescence

Fluorescence


7. The reaction of 2-chloropyridine with sodium ethoxide is

Elimination followed by addition

Electrophilic aromatic substitution

Addition followed by substitution

Nucleophilic aromatic substitution

8. When it is 8.30 A.M. on Wednesday of Greenwich, then:

It is 10.30 P.M. on Wednesday at New Delhi

It is 6.15 A.M. on Tuesday at New York

It is 3.30 P.M. on Wednesday at Sydney

It is 5.30 P.M. on Wednesday at Tokyo

9. Example of fermions are

Electron and proton

photon and proton

Electron and proton

Photon

10. What is the number of triangles in the given figure? <img src='./qimages/1943-10.jpg'>

12

20

8

14

11. Which of the following is the least dense metals?

Mercury

Lithium

Germanium

Platinum

12. Which of the following are the ingredients of gun metal?

Iron, zinc and sodium

Iron, copper and brass

Copper and Tin

Aluminum and Uranium

13. The minimum calculated distance of Mars from Earth is:

54.6 Million Km

401 Million Km

225 Million Km

95.5 Million Km

14. Which statement;is incorrect about the Z-DNA form:

It entails a left handed double helix winding to the left in a zig-zag pattern

The major and minor grooves show little difference in width

Certain conditions such as high salt and negative supercoiling induce it

Once induced, it usually persists longer and remains stable

15. The difference between the molecular weight of sucrose and that of the sum of the molecular weights of its components (glucose and fructose) is:

0

2

18

D)16

16. Different isotopes of an element are physically separated by the process of:

Ultra centrifugation

Filtration

Evaporation

Distillation

17. Proteogenomics is an approach of identification of proteins and peptides wherein:

Mass spectrometry based data are used for identification of novel peptides

Novel peptides are mined from customized genomic and transcriptomic databases

Mass spectrometry data are searched and compared against genomic and franscriptomics databases for the identification of novel peptides

Novel peptides are identified at the interface of proteomics and genomics approaches

18. The following is a potent alkylating mutagen that is used as a tool in genetic screens:

Nitosoamine

N-methyl formamide

Acridine orange

Nitroso-ethyl urea

19. Internal ribosome entry site (IRES) elements are present in the genome of

Rabies virus

Smallpox virus

Vaccinia virus

Poliovirus

20. The following are the reservoirs/vectors for Ebola and Marburg viruses:

Fruit Bats

Mosquitoes

Rodents

Migratory Birds

21. Mate pair information is not retained in this sequencing technique:

Solexa sequenGing

Sanger sequenCing

454 sequencing

SoLiD sequencing

22. There are 3 non-graduated gallons ABC:

Gallon A having max capacity of 7 litres is currently filled with 4 litres of water
Gallon B having max capacity of 5 litres is currently filled with 3 litres of water
Gallon C having max capacity of 3 litres is currently filled with 2 litres of water
How can you measure 1 liter of water in minimum number of steps?

Pour 1 litre of water from gallon A to gallon C

Pour water from gallon C to completely fill gallon B and leftover is one litre water

Step A followed by step B

Pour exactly 1 litre water from gallon C to gallon A

23. 30. This is what you have for an equation. The following are the numbers that you can use to fill in the brackets, if required with the use of a sign: 11, 13 15. Your correctly filled brackets should be:

(15 (13 (13





A or B

24. What function the transformer performs at a power station?

regulates heating of electric lines by stepping up the voltage

decreases heating of electric lines by stepping up the current

increases heating of electric lines by stepping up the voltage

decreases heating of electric lines by stepping down the voltage

25. The following type of chart is used to display the work break down structure of a project:

Dough nut chart

Gantt chart

Bubble chart

Radar chart

26. Which of the following programs does not take PDB file as an input:

RasMol

Chime

BLAST

PyMol

27. Beta-amyloid Plaques are associated with

Huntington disease

Alzheimer's disease

ALS

Parkinson's disease

28. The development of pollen in tapetum cells is prevented by the expression of an enzyme from Bacillus amyloliquefaciens

Hexokinase

ATPase

Cytochrome oxidase

Ribonuclease

29. You are studying DNA replication in an E. coli mutant, which has a partially defective DNA pollmerase. In vitro experiments using the mutant DNA polymerase gives an error rate of 10-6 as compared to the expected error rate of 10-6. Which of the following activities is the mutant polymerase likely to be missing, as compared to the normal polymerase

exonuclease

exonuclease

recombinase

polymerase

30. Biodegradable nanopartic1es have following features

Kill cells

Escape from immune system

Accumulate in the Gut

Unstable

31. Which of the following genetic elements insert at tRNA genes in their host chromosome

Genomic islands

IS elements

Plasmids

Prophages

32. Which of the following is the most common and stable confirmation for a polypeptide chain

Alpha helix

Beta pleated sheets

Anti-parallel beta pleated sheets

Tertiary structure

33. Which of the following statements is/are true regarding the distribution of ions during the resting membrane potential of a neuron

is more concentrated inside the cell

Na+ is more concentrated inside the cell

Ca+2 is concentrated more outside the cell

Na+ is concentrated more outside the cell

Only and are true

Only and are true

Only and are true

Only and are true

34. Inactivation of a gene that codes for a repressor protein which is involved in regulation of genes Y and Z leads to

Inhibition ofX,YandZtranscription

Constitutive expression ofX, Y and Z genes

Rapiddegradation ofX,YandZmRNA

Disappearance ofX, Y and Z proteins

35. Structures that have the same evolutionary origin although they may have different structures or functions are said to be

alogous

analogous

homologous

Non-homologous

36. In a mixture of proteins listed below, which should elute second in size-exclusion chromatography

cytochrome c Mr 13,000

immunoglobulin G Mr 145,000

ribonuclease A Mr 13,700

RNA polymerase Mr 450,000

37. Programmed cell death or apoptosis is

a genetically coded and regulated process

not associated with ischemia

inflammatory response

a result of multiple random events

38. The bacterial effector protein that induces hummingbird phenotype in cultured epithelial cells

Botulinum toxin

CagA

Staphylococcal protein A

LPS

39. Sickle cell anemia is a disease resulting from missense mutation. What amino acid is substituted at the original glutamic acid? This mutation affects which protein chain in the hemoglobin

Valine; beta hemoglobin

Valine; alpha hemoglobin

Methionine; alpha hemoglobin

Cysteine; beta hemoglobin


40. Which of the following is NOT a feature of a typical bacterial operon?

The genes are translated into a single polypeptide

The genes in the operon are transcribed into a single mRNA molecule

The genes frequently encode proteins that are involved in a single biochemical pathway

The genes are under the control of a single promoter

41.Which of the following amino acids will be the site of enzyme modification by phosphorylation?

Arginine

Cysteine

Phenylalanine

Serine

42. Ebola virus genome is

+ve ssRNA

-ve ss RNA

dsRNA

ss DNA

43. Which of the following drug inhibits DNA replication

Rifampicin

Puromycin

Oligomycin

5-Fluorouracil

44. Which of the following is a mobile electron carrier protein in the photosynthetic electron transport

Plastoquinone

Plastocyanin

Phycocyanin

DI protein

45. The following gene/locus when deleted from the X or V-chromosome can lead to misidentification of gender in forensic or prenatal analysis

a Holandric gene

Amelogenin

SRY gene

52. A famous biological sample repository based in the US is

ATCC

NCBI

NTTC

NIST

53. Thin layer chromatography can be used to distinguish between different amino acids. If a particular amino acid has"low solubility in the mobile phase used, then the amino acid

will have a low Rf value

will spend more time dissolved in the mobile phase than attached to the stationary phase

must have a high molecular mass

will move at a speed close to that of the solvent

54. Calcium channels in Endoplasmic reticulum of plants and animals are controlled by

cAMP

Inositol 1,4,5-triphosphate

cGMP

G-proteins

55. In isoelectric-focusing the following substances are used to give a pH gradient

Veronal

Tris

Polyaminopolycarboxylic acids

Phosphate buffer

56. Graft and tumor rejection are mediated primarily by

non-complement-fixing antibodies

phagocytic cells

helper T cells

cytotoxic T cells

57. Eukaryotic cells with DNA damage often cease progression through the cell cycle until the damage is repaired. This type of control over the cell cycle is referred to as

Proteosome control

Damage control

Anticyclin control

Checkpoint control

58. Area of the brain associated with speech is called:

Broca's area

Wernicke's area

Angular gyrus

Ventricles

59. Pharmacophore is a

Receptor

Molecular structure feature

Drug effect

Substrate effect

60. United Nations Educational, Scientific and Cultural Organization (UNESCO) celebrated the year 2014 as:

International Year of Bioinformatics

International Year of Crystallography

International Year of Molecular Biology

International Year of Structural Biology

61. Peroxiredoxins do not reduce

H202

Paraquat

Alkylperoxides

Peroxinitrites

62. Two-dimensional electrophoresis is a combination of which two techniques?

Isoelectric focusing and affinity chromatography

Ion-exchange chromatography and SDS-PAGE

Isoelectric focusing and SDS-PAGE

Isoelectric focusing and ion-exchange chromatography

63. Following labelled ATP can be used to label DNA or protein using a kinase

alpha-P-32 ATP .

P-32-inorganic phosphate

y-P32 ATP

B-P32 ATP

64. The mechanism that permits immunoglobulins to be synthesized in either a membrane-bound or secreted form is

allelic exclusion

codominantexpression

the one-tumltwo-turnjoining rule

differential RNA processing

65. Polynucleotide ligase joins two DNA molecules together by forming a covalent bond between

Two OH groups of adjacent strands

A 3'OH group and a P04 group

A P04 group and a OH group

Two carbon atoms of adjacent nucleotides on the same strand

66. Which of the following separates molecule according to their size

Gel-Filtration chromatography

Affinity chromatography

Isoelectic focusing

Ion exchange chromatography


67. Which of the following describes RNA interference

Antisense RNA molecules block the translation of mRNA molecules

Double-stranded RNA molecules are bound by proteins that block their translation

Double-stranded RNA molecules are cleaved by a nuclease into short interfering RNA molecules

Short interfering RNA molecules bind to the ribosome to prevent the translation of viral mRNAs

68. Which statement is scientifically correct about raw honey?

It retains footprints of all the components of the eco-social system of the beehive

It holistically entails benefits of pure honey, pollen, wax and other unknown biotic components and enzymes/peptides added by the bees and by their farmed Inicrobiota

It contains probiotic bacteria from the honey crop of bees

All of the above

69. One of the following is a regulatory protein

Gp120

integrase

Reverse transcriptase

Tat

70. The frequency of somatic mutation in Ig genes is greatest during

differentiation of pre-B cells into mature B cells

differentiation of pre-T cells into mature T cells

generation of memory B cells

antibody secretion by plasma cells

71. The methods used for locating transcription start site are

Gel retardation and foot printing

Northern analysis and RT-PCR

Primer extension and S1 nuclease mapping

Cloning of5' UTRs and DNA Sequencing

72. A person with lactose intolerance is most likely deficient in breaking the following chemical bond:

An ester linkage

A phosphodiester bond

An amide bond

A glycosidic bond

73. Severe Acute Respiratory Syndrome (SARS) virus belongs to the family

Picomaviridae

Coronoviridae

Adenoviridae

Abolaviridae

74. Which of the following processes is thought to underlie concerted evolution

Gene conversion

Lateral gene transfer

Programmed cell death

Transposition

75. Based on the time dependent changes in the fatty acid composition of a bacterial membrane as shown in the following figure, identify the abiotic stress treatment given to the bacterial culture

<img src='./qimages/1677-68.jpg'><br><br>

Heat stress

Salt stress

Cold stress

Oxidative stress