1. What is the concentration of in a solution of 0.lM NaOH?

10 power-12 M

10 power-13 M

10 power-14 M

10 power-10 M

2. How many ATP are produced during oxidation of one molecule of palmitic acid?

120

140

130

150

3. Which of the following is not a metalloprotein?

Phytochrome

Hemoglobin

Cytochrome

Erythropoietin

4. In bacteria, which of the following is not an effector?

cAMP

L-Arabinose

Allolactose

Lactose


5. Which one of the following inhibits platelet aggregation?

Leukotriene A4

Prostacyclin

Thrombaxane A2

Prostaglandin H2

6. One of the following is an 'endangered species'

Cycas beddomei

Santalum album

Petrocarpus marsupium

Terminalia bellerica


7. The antistreptolysin O titer is raised in infections caused by

Streptococcus sanguis

Streptococcus pneumonia

Streptococcus bovis

Streptococcus pyogens

8. The role of blood cells in phagocytosis was first demonstrated by

Louis Pasteur

Robert Koch

Elie Metchinkoff

Charles Chamberland

9. Aromatase enzyme converts

Estradiol to testosterone

Testosterone to estradiol

Estrogen to progesterone

Progesterone to estradiol

10. Chemoautotrophs obtain energy by oxidizing inorganic compounds. What is their source of carbon?

Glucose

Lactose

CO2

They reqUire no carbon source

11. Which of the amino acids is coded by only a single codon?

Glutamine

Tryptophan

Asperagine

Isoleucine

12. Rickettsia rickettsii is responsible for

Q-fever

Rocky Mountain Spot fever

Lyme disease

Typhoid fever

13. Serglycan is a proteoglycan expressed exclusively in

Tendon

Fibroblast

White blood cells

Embryonic epithelia

14. Which of the following introduces flagellated promastigotes into the skin of host?

Mosquito

Deer tick

Sand fly

Buffalo gnat


15. Which of the-following is the function of the contractile vacuole?

Site of food digestion

Contain specific enzymes that perform various functions

Maintain osmotic balance by continuous water expulsion

Site for photosynthesis

16. The term Variolation refers to

Generation of antibody variable regions

The attenuation of virulent organisms

Inoculation of scab material into small skin wounds

Removal of scab material from an individual with smallpox

17. Upon successful invasion of the pathogen, disease is progressed through a series of stages. Which of the following indicates correct order?

Prodermal, incubation,acute, convalescent, decline

Incubation, acute, prodernal, convalescent, decline

Incubation, prodermal, acute, decline, convalescent

Prodermal, convalescent, incubation, acute, decline

18. Defects in Neutrophil NADPH Oxidase system produce

Chediak-Higashi disease

Hashimoto's disease

Chronic granulomatous disease

Streptococcal infection

19. Which one of the following protozoan infection is detected by Sabin-Feldman dye test?

Trichomonas sp.

Toxoplasma sp.

Giardia sp.

Cryptosporodium sp.

20. Merozoites are stored in merosome. Membrane of merosome is derived from

Hepatocyte plasma membrane

Plasmodium plasma membrane

Mitochondrial membrane of hepatocytes

Plasma membranes derived from hepatocyte and Plasmodium

21. Circular RNA virus is

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Hepatitis D virus


22. Immunoglobulin that is present at highest concentration in normal individuals

IgM

IgG

IgD

IgE

23. Lesions of corner of mouth, lips and tongue are caused by deficiency of

Riboflavin

Thiamin

Calciferol

Cobalamine

24. Which one of the following does not derive from monocyte­macrophage lineage?

Follicular dendritic cells of lymph nodes

Neutrophils

Kupffer cells in liver

Monocytes in blood

25. DNA content per cell is highest in

Cells of Klinefelter syndrome individual

Cells of Down syndrome male individual

Cells of Down syndrome

Cells of Cri-du-chat syndrome female individual female individual

26. In an in vitro transcription assay y-p32-labelled NTPs are used. Which of the following statements is correct if transcription takes place in a direction?

Transcript remains unlabelled

Transcript will be labeled and the amount of radioactivity remains constant

Transcript will be labeled and the amount of radioactivity gets constantly increased

There will be an initial increase in radioactivity incorporation followed by sudden decrease

27. Which organization is concerned with 'biodiversity hotspots'?

Conservation International

United Nations

WWF

IUCN

28. Di George Syndrome results from a defect in

Purine nucleoside phosphorylase

Thymic development

CD3

WASP

29. The nature of Pathogen Associated Molecular Pattern (PAMP) that bind to human Toll-like Receptor located on phagosome membrane is

Single stranded viruses RNA of viruses

LPS from Gram negative bacterial cell wall

Double stranded RNA of viruses

Peptidoglycan from Gram positive cell wall

30. Integrins are a family of cell surface proteins that mediate adhesion between, cells and extracellular matrix. Which of the following is not an integrin?

CR3

CDllb

CD34

CD29

31. The effector function of an eosinophil is

Phagocytosis

Killing of antibody coated parasites

Activation of bactericidal mechanisms

Release of granules containing histamine

32. Terminal portion of Drosophila embryonic head which includes brain

Acron

Cephalon

Telson

Coxa

33. The four cells produced during spermatogenesis will have

2n number of chromosomes and will differ genetically from each other

n number of chromosomes and will be genetically identical to each other

2n number of chromosomes and will be genetically to each other

n number of chromosomes and will differ genetically from identical each other


34. Which of the following gets activated by Diacylglycerol

Protein Kinase C

Tyrosine Kinase

Protein Kinase A

MAP Kinase

35. What is the characteristic form introns have after being cut from a pre-mRNA

Circular form

Lariat shaped

Linear form

Theta structure

36. At high concentration of substrate, enzymes usually follow the kind of rate reaction

Zero order kinetics

First order kinetics

Second order kinetics

None of these

37. Immunity gained by a vaccine is

Natural active

Natural passive

Artificial active

Active Passive

38. Which one of the following is a noncoding long regulatory RNA?

sRNA

Xist RNA

Insolin HnRNA

Micro RNA

39. The phenomenon of Transvection is first observed in which organism

Homo sapiens

Mus musculus

Drosophila melanogaster

Caenorhabditis elegans

40. Bovine spongiform encephalopathy is associated with misfolding of

Prion

Myelin basic protein

GABA

Alpha-synnuclein

41. What is the genotype of the patients with Turner's syndrome

XY

XO

YO

XXO

42. The pituitary protein that binds and inactivates activin is

Inhibin

Luteinizing hormone

Follistatin

Follicle Stimulating Hormone

43. A cross is made between two individuals of genotype AABbCcDDee and AABbccDdee. What is the probability of producing the genotype AAbbccDDEe?

1/4

1/8

1/16

0


44. The condition caused by retrograde flow of blood into the internal spermatic vein resulting in the dialation of peritesticular vein is

Cryptorchidism

Virilisation

Amyloidosis

Variocele

45. Husband and wife are heterozygous recessive for albinism. If dizygotic (two-egg) twins are born to them, what is the probability of having same phenotype for pigmentation?

1/4

1/8

5/8

1/2

46. A population can only be in genetic equilibrium under conditions laid out in

The Hardy-Weinberg Law

The Watson-Crick Law

The Huxley-Darwin Law

The McClintok-Morgan Maxim

47. Gluconeogenesis is the process involved in the conversion of pyruvate to glucose. The process exclusively occurs in

Cytoplasm

Mitochondria

Plasma membrane

Endoplasmic reticulum

48. Which of the following form is responsible for the transport of dietary lipids from intestine?

Free fatty acid

Mixed micelles

Free triglycerides

Chylomicrons

49. The folloWing are the human pathogens. Which one of them is responsible for Whooping Cough?

Bordetella pertusis

Corynebacterium diphtheriae

Mycobacterium tuberculosis

Bordetella bronchiseptica

50. Animal diseases that can be transmitted to humans are termed as

Zoonoses

Enzootic

Epizootic

Panzootic

51. Paracrine factors that guide axonal growth cone and play important role in axonal migration

Neuropilin (neural crest migration)

Neurotropin (chemoattractant)

Neurotrophin (growth factor,keep neurons alive)

Nectrin


52. The enzyme hemolysin is secreted by all,the bacteria except

Pneumococci

Clostridia

Staphylococci

Streptococci

53. The following cells are not involved in phagocytosis

Microglial cell

Macrophages

Neutrophils

Natural-Killer cells,

54. The class of immunoglobulin is determined by

The J-chain

The variable chain

The T3-polypeptide complex chain

The heavy chain


55. TH cells are known to recognize the following antigen presenting cells

HLA Class I antigen

HLA class II antigen

Processed antigen

CD8 antigen

56. About 1000 (one thousand) E.coli cells were inoculated into a fresh LB medium. If the cells are allowed to grow for 10 generations what would be the total cell count?

1000 X 2power10

1000x10x2

1000 x 2power10/10

1000 X 10power2

57. Antibiotic that resembles like a end of charged tRNA molecules is

Streptomycin

Tetracycline

Puromycin

Sparsomycin

58. In a haploid organism the C and D loci are 8m.u apart. From a cross Cd x cD what proportion of the progeny will be all recombinants?

4

8

32

48

59. The bacteria that grow in low temperature are known as

Extremophile

Halophile

Psychrophile

Thermophile


60. If the DNA fragment size is between 200-2000 kb, which of the following vector is suitable for construction of genomic library?

Cosmid vector

BAC vector

YAC vector

PAC vector

61. Male and female yellow mice are crossed over several litters, a 2:1 ratio of yellow to wild-type (agouti) pups were produced. If the symbol "Y" represents the allele associated with yellow body color, which symbols below, accurately describe the genotypes of the offspring?

Yy and yy

YY and yy

Yy and Yy

YY and Yy

62. Which one of the following is not part of bacterial IS elements?

Terminal inverted repeats

Terminal direct repeats

TnPA

Drug resistant gene

63. The leader region (trpL) of tryptophan-specific mRNA functions as

Corepressor

Aporepressor

Activator

Attenuator

64. Calculate the length of double stranded DNA molecules of MW 3X 10 power7

26054

28094

48544

98868

65. The work of the following scientist is associated with replication of DNA

Crick

Barbara McClintoc

Stahl

Linus Pauling

66. The molecular weight of bacteriophage T4 DNA is 1.3 x 10power8 How many different proteins of MW 55,000 (55 kDa) could be coded by T4 DNA

153

120

130

123

67. The maximal rate of protein synthesis (amino acids per second) in bacterial cells is approximately

2

3-4

12-15

30-40

68. Which one of the following is not associated with nucleus of the cell?

Cajol bodies

PIKA

PML bodies

Centriole

69. Root-like projections through which a fungus obtains nourishment from the alga in lichens are known as

Rhizoid

Haustoria

Pyemia

Pycnidium

70. How many biodiversity hotspots extend into India?

2

1

3

5

71. Which of the following is an intracellular parasite?

Leishmania donovani

Schistosoma mansoni

Ascaris lumbricoides

Enterobius vermicularis

72. Which of the following gives information about phenotype but not genotype?

XhY

Hemophiliac man

Tall pea plant

Female carrier for color blindness

73. Drug chloramphenicol blocks

Cell wall formation

Transcription

Translational termination

Polypeptide chain elongation

74. What is the average size of the DNA fragment generated if digested with EcoRI?

4 power6

4 power4

4 power8

4 power2

75. Platelets are derived from

Erythroblast

Common lymphoid progenitor

Megakaryocyte

Plasma cells