Master of Science I (Biotechnology) Examination: Oct/Nov 2016
Semester II (Old CBCS)
SLR No. Day
Date Time Subject Name Paper
No. Seat No.
SLR SK
108
Tuesday
22/11/2016
10.30 AM
To
01.00 PM
Molecular Cell Processing
C
III
es Instructions: Section I is compulsory.
Answer any four questions from Section -II.
All question carry equal marks.
Figures to right indicate full marks.
Draw neat and labeled diagrams.
Total Marks: 70
Section- I
Q.1 Rewrite the following sentences by selecting correct answers from given
alternative.
07
statement is true of DNA damage.
Most DNA damage is repaired
by the cell
All DNA damage result in
diseases such as cancer
All DNA damage is caused by
physical agents
Most DNA damage is
advantageous to the cell
RNA primer necessary for DNA replication
The RNA prime is necessary
for the activity of DNA ligase.
The RNA primer creates the
and ends of the strand
DNA polymerase can only add
nucleotides to RNA molecules
DNA polymerase can only add
nucleotides to an existing
strand.
The common demonization occurs during DNA damage
Thymine dimer Adenine dimer
Guanine dimer None
During the process of transcription, of the following is produced
H2O ATP
mRNA DNA
DNA repair mechanism is absent in
Nuclear genome Mitochondrial genome
Chloroplast genome Both b c
The peptide chain grows on site
A P
E Both a b
Transcription termination occurs by
Rho-dependent Pho-independent
Sigma factor Both a b
Page 1 of 2
Define the following terms: 07
Topoisomer
Activators
SOS repair
50 S ribosome
RNA Polymerase
Nitrosylation
Arthur Kornberg enzyme
Section II
Answer Any Four
Q.2 Write a note on base excision and recombination repair with neat labeled diagram. 14
Q.3 Write a note on different types of intron splicing and add a note on spliceosome. 14
Q.4 Describe the structure, assembly and function of each subunit of DNA pol III with
neat labeled diagram.
14
Q.5 What is oriC? Explain the eukaryotic DNA replication with neat labeled diagram. 14
Q.6 Answer any TWO of the following: 14
Write a note on different types RNA molecules
Explain the recombination process
Write a note on post transcription modification of eukaryotic mRNA.
Q.7 Write shorts notes on (Any 14
Prokaryotic gene structure
Eukaryotic ribosome subunits
Translation initiation factors