Master of Science I (Biotechnology) Examination: Oct Nov 2016
Semester II (New CBCS)
SLR No. Day
Date Time Subject Name Paper
No. Seat No.
SLR SK
104
Tuesday
22/11/2016
10.30 AM
To
01.00 PM
Molecular Cell Processing
C
VII
es Instructions: Section- I compulsory.
Answer any four questions from Section-II.
Figures to the right indicate full marks.
Answer to the Section I and Section II are to be written in the
same answer book.
Total Marks: 70
Section- I
Q.1 Rewrite the following sentences by selecting correct answers from given
alternative.
07
is true of DNA damage.
Most DNA damage is
repaired by the cell.
All DNA damage results in
diseases as cancer
All DNA damages is caused
by physical, chemical or
biological agents
Most DNA damage is
advantages to the cell
One complete helical turn of Z form of DNA has
nucleotides.
9 10
11 12
protein seals the nucleosome.
H1 H2A
H2B None of these
Lactose operon has structural genes.
Lac Lac Lac-a Lac Lac Lac-y
Lac Lac Lac-Z Lac Lac Lac-b
The first step in translation is
Transfer of amino acid Initiation of synthesis to t-RNA
Activation amino acid None of these
site on DNA is responsible for binding of enzyme RNA
polymerase during transcription process.
Operator Promoter
Regulator Enhancer
The type of mutation most commonly associated with exposure to UV light
is
Thymine dimerization Base deamination
Depurinization Base deletion
Page 1 of 2
Define the following terms: 07
Okazaki fragments
Primary transcript
Replication fork
Cot curve
Replicon
Solenoid
Heterochromatin
Section-II
Q.2 Explain in detail about replication in prokaryotes and DNA proof reading with a
neat labeled diagram.
14
Q.3 Write a note on base excision and recombination repair with a neat labeled
diagram.
14
Q.4 Describe the process of translation in prokaryotes and add a note on inhibitors of
translation.
14
Q.5 Explain in detail packing and organization of eukaryotic genome with a neat
labeled diagram.
14
Q.6 Answer any TWO from the following: 14
Explain about Cot curve.
Write a note on different types of RNA.
Write about holiday model of recombination.