FACULTY OF PHARMACY
B. Pharmacy IV Year II Semester (Main) Examination
Subject: Pharmaceutical Biotechnology
Time: 3 Hours Max.M arks: 70
Note: Answer all questions. All questions carry equal marks.
1 Explain the production of insulin by rDNA technology.
OR
Give a brief account of Restriction Endonucleases Cloning strategies.
2 Give an account of microbiological assay of Vitamin B12.
OR
Give an account of immobilization of enzymes and their applications.
3 Define and classify vaccines. Write the preparation and purified forms of diphtheria
vaccine.
OR
Give an account of
Viral vaccines
ii) Immunodiagnostics
4a) Describe the collection, processing and storage conditions of whole human
blood.
ii) Write the preparation of dried human plasma.
OR
What are the ideal requirements of plasma substitutes? Write the fermentative
production of dextran.
5 Give an account of microbial transformation of steroids.
OR
Describe the production of monoclonal antibodies. Add a note on their applications.