FACULTY OF PHARMACY
B. Pharmacy 4/4 II Semester (Makeup) Examination, September 2017
Subject Pharmaceutical Biotechnology
Time 3 hours Max. Marks 70
Note Answer all questions. All questions carry equal marks.
1 Explain the manufacture of interferons by rDNA technology.
OR
Explain the following
Cloning strategies
ii) Interleukins
iii) Gene Expression in Recombinant DNA
2 Give an account of methods for the immobilization of enzymes. Add a note
on their applications.
OR
Explain the fermentative production of streptomycin. 10
ii) Write a short note on Biomass. 4
3 Explain the manufacture, purification and standardization of Diptheria
antitoxin.
OR
Write the preparation of
DPT vaccine
ii) Polio vaccine
4 What are the properties of an ideal plasma substitute? Give an account of
preparation of dextran.
OR
Explain the preparation of extracts from
Pituitary gland ii) Pancreas
5 Give an account of Microbial transformation of steroids.
OR
Explain the method of preparation of monoclonal antibodies. Add a note on
their applications.