B. Pharmacy 3/4 II-Semester (Main) Examination
Subject Pharmaceutical Chemistry (Chemistry of Natural Products)
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Discuss the constitution of fructose.
Explain one method of converting an aldose to a higher ketose.
Write a note on rancidity.
OR
Discuss the chemistry of glucose.
Define and write the principle, method of determination and the significance of
Iodine value Saponification value
2 Classify proteins with examples.
Explain acid synthesis by
Erlen meyer Azelactone method
Phthalimido malonic ester method
Write a note on anti thyroid drugs.
OR
Discuss the constitution of Oxytocin.
Write any two methods in the determination of N-terminal amino acid in a
polypeptide chain.
Write the biological significance of Insulin.
3 What are terpenoids? Write in detail the general methods for structure elucidation
of terpenoids.
Discuss the chemistry of menthol. Add a note on stereoisomerism.
OR
Discuss the constitution of Quercetin.
Outline the synthesis of Citral Amygdalin (2x3.5)
4 Explain the methods to determine the functional nature of oxygen in alkaloids.
Discuss the chemistry of caffeine.
OR
Establish the constitution of meroquinine.
Elucidate the structure of papaverine.
5 Write chemistry and physiological role of
Corticosteroids Bile acids
OR
Differentiate between cardenolides and bufadienolides. Write the chemistry of
digitalis glycosides. Add a note on mechanism of action.
Write the structure and uses of
Diosgenin Progesterone
Write a note on Oral contraceptives.