FACULTY OF PHARMACY
B. Pharmacy 3/4 Year II Semester (Supplementary) Examination
Subject: Pharmaceutical Chemistry (Chemistry of Natural Products)
Time: 3 Hours Max.Marks: 70
Note: Answer All questions. All questions carry equal marks.
1 What are carbohydrates, classify and give the color reactions. 6
Write about the pyranose structure of glucose. 8
OR
Discuss the structural features and chemical reactions of fructose. 8
What is muta rotation and explain the mechanism. 6
2 Discuss various methods of sequence analysis of polypeptides. 8
Write the structural features and the therapeutic importance of oxytocin. 6
OR
Discuss the chemistry and important structural features of insulin. 6
Discuss the general method of synthesis of a protein or polypeptide. 8
3 Write the chemical properties and therapeutic benefits of flavonoids. 6
Write about chemistry of citral. 8
OR
Write the synthesis of menthol. 6
Give the sources, chemistry and spectral characters of arbutin. 8
4 Explain the significance and difference between Zeisel method and
Herzig Meyer method. 6
What are oxidative products of quinine and elucidate the structure of
meroquinene. 8
OR
Give the sources, uses and elucidate the structure of ephedrine. 9
Write the general method of alkaloid isolation. 5
5 What are cardiotonics, classify with examples and discuss the chemistry and
mechanism action of digitalis. 6
Write the chemical structure and sources of
Hecogenin ii) Diosgenin 4
Write the structural features of corticosteroids with examples. 4
OR
What are bile acids and give the therapeutic importance of bile acids. 5
Give an informative note about oral contraceptives. 5
Give the chemical structure and uses of
Stropanthidin ii) Testosterone 4