FACULTY OF PHARMACY
B. Pharmacy 4/4 I Semester (Suppl.) Examination, April 2017
Subject: Dosage Formulations Design (Pharmaceutics III)
Time: 3 Hours Max.Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Explain in detail about the importance of various physicochemical properties of drug
substance in designing a quality and stable dosage form. 14
OR
What are the different pathways of degradation of pharmaceutical products and how
they can be protected from degradation? 14
2 Enlist the approaches that are used for formulating sustained release oral products
and discuss in detail. 14
OR
What are the advantages associated with micro capsules? Describe the preparation
by non-solvent addition. 7
Explain the air suspension technique for preparing micro capsules. 7
3 Enumerate potential advantages of TDDS with examples. Explain the evaluation
methods of TDDS. 14
OR
Write about preparation and characterization of liposomes. 8
Explain about Pilo 20 and Pilo 40. 6
4 Define process validation. Write briefly about types of process validation. 7
Write a note on GMP. 7
OR
Explain in detail about the methods to enhance bioavailability of drugs. 14
5 Explain the difference between QA and QC. What are the various sources of
variation? 7
Explain the QA at startup. 7
OR
Explain briefly the role of QA in the manufacture of tablet dosage forms. 7
Write short notes on QC charts. 7