FACULTY OF PHARMACY
B. Pharmacy 4/4-Year I-Semester (Non-CBCS) (Main) Examination,
November 2018
Subject Dosage Formulation and Design (Pharmaceutics III)
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Describe the following physical properties and their effect on preformulation
studies
Particle size and shape ii) Solubility iii) Polymorphism 8
Explain the significance of preformulation studies in the formulation of dosage
forms. 6
OR
Write about different chemical properties of drug and their influence
on formulation and stability of products. 14
2 Explain the concept of sustained release dosage forms and describe the
approaches based on dosage form modification. 7+7
OR
Write a note on various microencapsulation techniques and their applications.
3 Write about the various approaches used in fabrication of TDDS and explain the
in vitro evaluation of TDDS. 14
OR
Explain the concept of ocular drug delivery system and write in detail about
design of occuserts.
4 Describe in detail about different bioavailability enhancement techniques. 14
OR
Write in detail about the concept of GMP in pharmaceutical production.
5 Define quality control and quality assurance. Describe raw material control in
detail. 14
OR
Explain in detail about master formula record and batch production record.