M.Sc.(Biotechnology) (Semester- IV) (CBCS) Examination, 2017
Molecular Medicine
Day Date: Monday, 24-04-2017 Max. Marks: 70
Time: 10.30 AM to 01.00 PM
Instructions
All question of Section 1 are compulsory.
Answer any Four questions from section II
All questions carry equal marks.
Draw neat and labeled diagrams wherever necessary.
SECTION I
Q.1 Rewrite the sentences after choosing the correct answer
from the given.
07
The α-globin gene of haemoglobin is located on chromosome
number………..
11 12
16 18
..... gene is mutated in cystic fibrosis
CFTR Actin
Cadherin Fibrin
……….. is defined as compounded that demonstrates the
desired biological activity on molecular target.
Lead Genome
Mercury Iron
SCID is an example of ………. gene therapy
Ex-vivo In-vivo
In-situ All of these.
MHC Antigen in human is known as……….
HLA ALC
ASB HSB
Page 1 of 2
Stem cell exhibits…… properties.
Only potency
Potency and self renewable
Potency and non renewable
Only self-renewable
I
In DNA fingerprinting………….repeated sequences of DNA is
used.
Variable number of tandem repeats
Verified number of tandem repeat
Versatile number of transverse repeat
Variable number of transverse repeat.
I
B Define the terms 07
Stem cells.
Gene therapy
Amniocentesis.
DNA fingerprinting.
Microarray.
Plasmids
Sickle cell anemia
PART II
Answer any four of following
Q2 Write a brief account on Stem cells and its properties. 14
Q3 Explain in detail Cystic fibrosis with labeled diagram 14
Q4 Write a note on gene therapy and its types. 14
Q5 Answer any TWO of the following. 14
Explain in details prenatal diagnosis and its methods.
ii) Explain the methods of structure based drug discovery.
iii) Describe in details route of administration of drugs.
Q6 Write short notes on any TWO of the following 14
Write a note on induced pluripotent stem cells.
ii) Describe alzheimer's disease.
iii) Explain in-vivo and ex-vivo gene theraphy