M.Sc. (Bioinformatics) (Semester-IV) (CBCS) Examination, 2017
MOLECULAR MEDICINE
Day Date: Wednesday, 26-04-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
N.B. All questions of Section-I are compulsory.
Answer any Four questions from section II.
All questions carry equal marks.
Draw neat and labeled diagrams wherever necessary.
SECTION I
Q.1 Rewrite the sentence after choosing the correct answer
from the given.
07
In DNA fingerprinting repeated sequences of DNA is
used.
Variable number of tandem repeats
Verified number of tandem repeat
Versatile number of transverse repeat
Variable number of transverse repeat
Stem cell exhibits properties.
Only potency
Potency and self renewable
Potency and non renewable
Only self-renewable
MHC Antigen in mouse is known as
HLA H-2 ASB HSB
The -globin gene of haemoglobin is located on chromosome
number
11 12 16 18
Gene is mutated in cystic fibrosis.
CFTR Actin Cadherin Fibrin
Stem cell exhibits properties.
Only potency
Potency and self renewable
Potency and non renewable
Only self-renewable
Hematopoietic stem cells
Pluripotent Totipotent
Unipotent Oligopotent.
Page 1 of 2
Define the terms: 07
Totipotency
Recombination
Amniocentesis
DNA fingerprinting
Microarray.
Plasmids
Sickle cell anemia
SECTION II
Answer any four of the following:
Q.2 Write a brief account on Stem cells and its properties. 14
Q.3 Explain in detail Cystic fibrosis with labeled diagram. 14
Q4 Explain in detail steps involved in during discovery and its design. 14
Q.5 Answer any two of the following 14
Give an account on Huntinston's disease.
Explain different nature and sources of drug.
Explain in brief human genome project.
Q.6 Write Short notes on any TWO of the following 14
Write a note on induced pluripotent stem cells.
Describe alzheimer's disease.
Explain in-vivo and ex-vivo gene therapy.