Master of Science II (Microbiology) Examination: Oct Nov 2016
Semester III (New CBCS)
SLR No. Day
Date Time Subject Name Paper
No. Seat No.
SLR SO
631
Friday
18/11/2016
02:30 P.M
to
05:00 P.M
Immunology
Immunotechnology
C
X
Instructions: Part I is compulsory.
Attempt any four questions from Part II.
Part I and Part II should be written in same answer book.
Figures to the right indicate full marks.
Total Marks: 70
PART I
Q.1 Rewrite the following sentences by selecting correct answers from given
alternative.
14
Humoral Immunity is mediated by
B cells macrophages
dentritic cells cytotoxic T cells
is secondary lymphoid organ.
MALT Spleen
Lymph node All of these
The MHC in mouse called H2 gene complex is located on chromosome no.
in mice.
16 6
14 17
Bacteria, neoplastic cells, virus infected cells as well as intracellular parasites
containing cells are destroyed by
T lymphocytes NK cells
B lymphocytes Phagocytes
Cell medicated immunity protects the body from pathogenic agents.
Intracellular extracellular
both a and b None of these
Generally antibodies produced against the pathogen are
Monoclonal polyclonal
homogenous a b both
In an autoimmune Mastheniagravic autoantibodies are produced against
RBC WBC
Thyroid hormones acetyl choline receptors
An antibody response to foreign tissue is suppressed in which of the following
phenomenon?
immune tolerance immune enhancement
autoimmunity none of these
Activated B lymphocyte after antigenic stimulus get differentiated into
Plasma and memory cells Plasma and CD4 cells
NK cells and plasma cells NK cells and memory cells
10) In an auroimmune disease idiopathic thrombocytopic purpura autoantibodies are
produced against
RBC WBC
Thyroid hormones platelets
11)MHC is present in
only human only mouse
human mouse all mammals
12) Cytokines are
low molecular wt proteins high molecular weight
both a and b none of these
13) Histamine is
Primary mediator of anaphylaxis atopen
secondary mediator of anaphylaxis allergen
14) Mast cell
are found in lymph nones are phagocytic
circulate in the blood stream Release histamine
PART II
Attempt any Four questions from Part II.
Q.2 Write essay on "Primary and Secondary lymphoid organs". 14
Q.3 Write in detail on "Structure and function of MHC gene complex in human and
mouse".
14
Q.4 Write in detail on "Diagnosis of SLE and other autoimmune diseases by Anti nuclear
antibody test".
14
Q.5 Write short answers any Two: 14
Natural killer cells
Innate immunity
Chemokines
Q.6 Write short notes on any Four of the following: 14
T lymphocyte and its types
Macrophage
Immunodiagnosis of tumers
HLA typing
Differentiate between normal and cancer cell
Alpha fetoprotein