M.Sc. (Semester III) (CBCS) Examination Oct/Nov-2017
Microbiology
IMMUNOLOGY IMMUNOTECHNOLOGY
Day Date: Tuesday, 21-11-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
Instructions: Part- Questions No.1 Compulsory.
Attempt any 4 questions from Part II.
Figures to the right indicate full marks.
Answer to the Part I and Part II are to be written in same answer booklet
only.
PART I
Q.1 Choose the correct alternative given in the bracket. 14
Immunity mediated by antibodies produced in the human of body fluids such
as plasma or lymph is known as
Cell mediated Humoral
Natural active Artificial active
IgE
Is abundant in saliva
Binds strongly to mast cells
Cannot bind to macrophages
Activates the complement cascade
The failure to reject or inactivate self reactive cells results
Autoimmunity Positive selection
Negative selection Suppression
Contact dermatitis and allergy of infection are an example of
hypersensitive reaction.
Type I Type- II
Type III Type IV
secondary lymphoid organ
MALT Spleen
Lymph node All of these
helper cells carry molecules as its specific marker
CD4 CD8
CD9 CD3
T cell surface receptors for antigen partly
Cytokines MHC
Antibody ADCC
The MHC is a collection of genes located on chromosome in
humans
15 17
6 None of these s
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SLR-MQ-594
In an autoimmune disease pernicious anaemia, antibodies are produced
againsta)
Folic acid Vitamin B12
Intrinsic factor None of these
10) has maximum phagocytic activity
Mast cells Basophil
Monocyte Macrophage
11) MHC class I molecules are present on surface of
Only platelets All nucleated cells
Only antigen presenting cells RBCs
12) In case of cancer TNM stands for
Tumour, Node, Metastases.
Temperature, Metabolism, Nutrition.
Tumour, Nerve, Metastases.
Tumour, None, Metastases. s
13) Cytokines
are lymphokines
are monokines
help to control regulate immune response
all of these
14) Autoantibodis against acetyl choline receptors are produced in
Rheumatoid arthritis Myasthenia gravis
Goodpasture's syndrome Pernicious anaemia
PART II
Q.2 Write in detail on "Natural (Innate) and acquired immunity and differentiate
between active and passive immunity"
14
Q.3 Write in detail on "Major histocompatibility antigens and genes and describe
methods of HLA typing"
14
Q.4 Write essay on "Properties and Immuno regulatory role of Cytokines". 14
Q.5 Write in short on any Two of the following: 14
Application of immuno technology in diagnostic medicine.
Differentiate between Cancerous cell and normal cells.
Theories of origin of autoimmunity
Q.6 Write short notes on any TWO of the following: 14
Structure and function of T cell receptors
Physical and mechanical factors in immunity.
Immune system in vertebrate and non-vertebrate.
Types of lymphocytes.
Alpha fetoprotein.
Function of lymphoid organs.