Master of Science II (Zoology) Examination: Oct Nov 2016
Semester III (New CBCS)
SLR No. Day
Date Time Subject Name Paper
No. Seat No.
SLR
SN-736
Wednesday
16/11/2016
02.30 PM
To
05.00 PM
Molecular Cytogenetic
C
IX
Instructions: Q.1, 2 6 are compulsory.
Answer any two questions from Q.3, 4 5
Total Marks: 70
Q.1 Multiple choice questions (per question 2 marks) 14
In Prokayotes Chromatin is formed of
nucleic acid and proteins nucleic acids and carbohydrates
nucleic acids and lipids only nucleic acids
Nucleosome core particle is a of basic histones.
Tetramer Hexamer
Octamer Decamer
Tip of the chromosomes are called
Euchromatin heterochromatin
allochromosome telomere
The nucleotide sequences in eukaryotic DNA that encode a polypeptide are
called
exons codons
histones introns
Monosomic condition is represented by
2n+1 2n-1
2n-2 2n+2
An individual with chromosomes compliment 47, XXY is known as
syndrome.
Turner Klinefelter
Edwards Down
"Buckle out" or compensation loop in normal homologous chromosome is
formed during
Duplication Deletion
Translocation Inversion
virus-mediated bacterial DNA transfer of genetic material.
Transformation Conjugation
Transduction Translocation
The sex in Drosophila is determined by
X and Y chromosomes X/A ratio
Z and W chromosomes haploidy
Q.2 What is nucleosome? Describe how eukaryotic genome is packed? 14
Q.3 Answer the following:
Describe the molecular basis of cellular check points during cell cycle. 07
Describe the chromosomal theory of sex determination in humans? 07
Q.4 Explain the following:
Describe cytogenetic effects of ionizing radiation 05
Transposable elements and their features 05
Automated Karyotyping 04
Q.5 Explain in short:
Chromosomal Structural aberrations 07
DNA Sequencing by Sanger 07
Q.6 Write short notes on any Four of the following: 14
Plasmid
Imprinting
C-value paradox
Pedigree analysis
Mitochondrial genome
Sickle cell anaemia