M.Sc. (Semester III) (CBCS) Examination Oct/Nov-2017
Zoology
MOLECULAR CYTOGENETICS
Day Date: Thursday, 16-11-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
Instructions: Question number 2 and 6 are compulsory.
Attempt any two from Question No. 4 and 5.
Q.1 Multiple choice questions. (Per question 2 marks) 14
In Eukayotes Chromatin is formed of
Nucleic acid and proteins
Nucleic acids and carbohydrates
Nucleic acids and lipids
Only nucleic acids
Nucleosome core particle is a of basic histones.
Tetramer Hexamer
Octamer Decamer
Genetically inactive areas of chromosomes are
Euchromatin Heterochromatin
Allochromosome Telomere
The intervening nucleotide sequences in DNA are
Exons Codons
Histones Introns
Monosomic condition is represented by
2n+1 2n-1
2n-2 2n+2
An individual with chromosomes compliment 47,XXY is known as

Turner Klinefelter
Edwards Down
"Buckle out" or compensation loop in normal homologous chromosome is
formed
Duplication Deletion
Translocation Inversion
is virus medicated bacterial DNA transfer to genetic material.
Transformation Conjugation
Transduction Translocation
The sex ratio of a normal female in Drosophila is
0.5 1.0
1.5 0.2
Q.2 What is nucleosome? Describe how eukaryotic genome is packed? 14
Page 2 of 2
SLR-MT-691
Q.3 Answer the following.
Describe the molecular basis of cellular check points during cell cycle. 07
Describe the Genic balance theory of sex determination? 07
Q.4 Explain the following.
Describe cytogenetic effects of ionizing radiation. 05
Transposable elements and their features. 05
FISH. 04
Q.5 Explain in short
Chromosomal numerical aberrations. 07
DNA Sequencing by Sanger. 07
Q.6 Write short notes on any four of the following: 14
Transformation in bacteria.
Imprinting.
C-value paradox.
Centromere.
Yeast genome.
Sickle cell anaemia.