Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER VIII • EXAMINATION WINTER • 2016
Subject Code: 2280003 Date: 24-11-2016
Subject Name: Pharmaceutical Chemistry-X (Medicinal Chemistry
Time: 02:30 pm 05:00 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 Define and classify Antihyperlipidemic Agents. Give the structural
Formula of any three drugs belonging to different class. 06
Discuss the SAR among HMG CoA Reductase inhibitors. 05
Give the method of synthesis of
Clofibrate Warfarin 05
Q.2 Define and classify Diuretic Agents. Give the structural formula
of any three drugs belonging to different class. 06
Discuss the SAR among
Thiazide Diuretics Sulfamoyl Benzoic acid derivatives. 05
Give the method of synthesis of
Ethacrinic acid Furosemide 05
Q.3 Write short note on Coagulants and Anti- Coagulants 06
Write informative note on Anti platelet Agents 05
Discuss detail about Plasma expanders 05
Q.4 Write detail note on Cardio tonic Agents 06
Write informative note on Anti-obesity Agents 05
What do you understand by Immunomodulators? 05
Q.5 Define and classify Hypoglycemic Agents.
Illustrate your answer with specific examples 06
Give the method of synthesis and uses of
Glimipride Pioglitazone 05
Give the synthesis and uses of
Methimazole Tolbutamide 05
Q.6 Explain in detail the nomenclature and stereochemistry of
Steroidal Compounds. 06
Write Short note on Adrenocorticoids 05
Write brief note on Sex Hormones. 05
Q.7 Define and classify Antihypertensive Agents with suitable examples. 06
Give the synthesis and uses of
Amlodipine Atenolol 05
Write informative note on Anti angial Agents.
Give the synthesis of Isosorbidedinitrate 05