Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: 2220001 Date: 19/12/2018
Subject Name: Physical Pharmacy
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Define and Explain phase rule. Discuss phase diagram for one component system.
06

Write a note on Liquid crystals and Glassy state.
05

Discuss in details about binding forces between molecules.
05
Q.2

Define Solubility. Describe the influence of surfactants on solubility.
06

Explain kinetic properties of colloids.
05

Describe solubility of gases in liquids.
05
Q.3

Define emulsion and classify with suitable examples. Explain the theory behind stability of emulsion.
06

What is meant by controlled flocculation? Discuss the various means by
which controlled flocculation can be achieved.
05

Explain Sedimentation Parameter of suspension in detail.
05
Q.4

Define micromeritics. Explain method for determining particle surface area of porous materials.
06

Discuss the derived properties of powder.
05

Describe briefly optical microscopy for particle size determination with its advantages and disadvantages.
05
Q.5

What is Surface tension.Enumerate the methods for the determination of surface andinterfacial tension. Explain capillary rise method.
06

Explain about Solute solvent Interaction for polar and non polar solvent.
05

Write an note on HLB
05
Q. 6

Differentiate between(i) ideal and real solution Lyophilic colloids and Lyophobic colloids.
06

Give the pharmaceutical applicatios of complexes in dosage forms.
05

Write a note on Spreading coefficient.
05
Q.7

Classify various instruments for measurement of viscosity. Descuss on rotating spindle type viscometer .
06

What is thixotropy and antithixotropy. Give its Pharmaceutical applications.
05

Define and explain: Angle of repose and Carr's Index with their
pharmacopoeial specification.
05