Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm SEMESTER- II • EXAMINATION SUMMER 2017
Subject Code: 220006 Date: 15/06/2017
Subject Name: Physical Pharmacy
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Classify interfaces, show that surface tension is a force per unit length and also as surface free energy change per unit area increase.
06

Enumerate methods to determine surface and interfacial tensions.
05

Give applications of spreading coefficient.
05
Q.2

Compare the properties of colloidal sols.
06

Write in brief on (any ultra-centrifuge, wetting (iii)adsorption at solid interfaces
05

Write on stability of colloidal systems.
05
Q.3

Write on importance of the following (any particle size distribution,(ii) number and weight distribution.
06

Explain in brief methods to determine particle size.
05

Enumerate derived properties of powders.
05
Q.4

Explain Newtonian law of flow.
06

Discuss the temperature dependence of viscosity of liquids.
05

How does thixotrophy differ from non Newtonian systems? Give applications of rheology.
05
Q.5

Differentiate between flocculated and deflocculated systems.
06

Write on significance of sedimentation parameters.
05

Write in brief on any one: controlled flocculation, techniques of suspension preparation.
05
Q. 6

Give crystalline states of solids
06

Write in short on any one: x-ray diffraction, polymorphism, properties of liquid crystals.
05

Write on liquefaction of gases.
05
Q.7

How is measurement of isotonicity done?
06

Write in brief on any one: cosolvence, effect of pH on solubility, partition coefficient
05

Write on theories of emulsification.
05