FACULTY OF PHARMACY
B.Pharmacy IV/ I-Semester (Suppl.) Examination
Subject Medicinal Chemistry II
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Define and classify Local anaesthetics with suitable examples.
Write the synthesis and mode of action of the following drugs.
Lidocaine Pethidine Ibuprofen
OR
Classify the non-steroidal anti-inflammatory agents and explain their
mode of action.
Describe the SAR of Local anaesthetics belongs to p-amino benzoic acid
derivatives.
2 Classify the antibiotics with examples and mention their mode of action.
Outline the synthesis of following drugs.
Methorexate ChloramphenicalO
R
Write the SAR of penicillins.
Outline the synthesis, mode of action and uses of
Norfloxacin Sulphamethoxazole.
3 Classify antimalarial drugs with examples.
Outline the synthesis, IUPAC name and therapeutic uses of following drugs.
Primaquine Ethambutol Metronidazole
OR
Write the mode of action and SAR of 4-amino quinolones.
Write in detail about the standard drugs used in tubercular therapy.
4 Enumerate the radius Benzodiazepines with their structure and write their mode of
action.
Describe the SAR of Benzodiazepines and Barbiturates.
OR
Write the IUPAC name, synthesis and uses of following drugs.
Phenytoin Chlorpromazine Halothane
Write a note on phenothiazines.
5 Write the structure of Riboflavin and ascorbic acid. Describe their biochemical role
and uses.
What are essential amino acid? Enumerate them with the chemical structure and
mention their biochemical role.
OR
Write the structure, uses and biochemical role of any two fat soluble vitamins.
Write a note on the development of protein drugs.