FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) I-Semester (Main) Examination, February 2018
Subject: Cellular and Molecular Pharmacology
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Describe the structure and functions of any four cell organelles. 8
Write a note on apoptosis. 7
2 Discuss in brief about JAK-STAT Pathway and MAP kinase pathway.
Write a note on nuclear receptor. 5
3 Describe the various types of gene delivery techniques. 8
Write a note on PCR and SDS-PAGE.
4 Describe in detail about genetic variations in drug metabolism . 10
Write a note on metabolomics. 5
5 Explain about the basic equipments used in cell culture lab. 10
Write a note on calcium influx assays. 5
6 Explain any two gene sequencing techniques.
Write a note on nitric oxide and cGMP.
7 Describe the various types of cloning vectors. 9
Write a note on immunotherapeutics. 6
8 Explain the principle and applications of flow cytometry. 6
Write a note on biosimilars and glucose uptake assays.