FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) I Semester (Main Backlog) Examination,
February 2019
Subject: Cellular and Molecular Pharmacology
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Explain structure and function of cell organelles and genome organization. 8
Explain how cell cycle will be regulated? 7
2 What do you understand about secondary messenger? 8
Write descriptive notes on tyrosine kinase and nuclear receptors. 7
3 Explain in detail various types of intracellular signaling pathways (Cyclic AMP,
MAOK, JAK and STAT). 15
4 Write a note on principle and application of genomic tools. 8
What do you understand about DNA electrophoresis? 7
5 Write a note on gene mapping and cloning of disease gene. 8
Write a note on metabolomics and proteomics. 7
6 Explain in detail various types of gene transfer techniques. 8
Write a descriptive note on gene sequencing and micro array technique. 7
7 Write a descriptive note on glucose uptake and calcium influx assay. 8
Explain various types of cell culture techniques. 7
8 Write a note on principle and application of various cell viability assays. 10
Write a note on Biosimilars. 5