M.Sc. (Semester (CBCS) Examination Oct/Nov-2017
Genetics
CLINICAL BIOINFORMATICS
Day Date: Thursday, 23-11-2017 Max. Marks: 70
Time: 10.30 AM to 1.00 PM
Instructions: Part Questions 1 is compulsory.
Attempt any four questions from part -II.
Figures to the right indicate full marks.
Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Section-I
Q.1 Rewrite the following sentences by using correct alternatives: 07
also known as drug safety is the pharmacological science
relating to the collection, detection, assessment, monitoring, and
prevention of adverse effects with pharmaceutical products.
Clinical trial Pharmacovigilance
CDM Pharmacology
is an affordable mapping and spatial analysis tool that allows
you to easily produce publication-quality thematic maps.
Microarray MapViewer
Ensemble GEO
CPT is a registered trademark of the Medical Association.
American Indian
Australian All of above
resource provides viral and viroid genome sequence data
and related information.
ViPR Ensembl
dpSNP OMIM
can be used to filter, reformat, or trim your genomic and
metagenomic sequence data.
HTQC QPLOT
PRINSEQ FASTX
R is an language; users typically access it through a
command-line interpreter.
Object oriented Structure oriented
Interpreted All
is the total number of metabolites present within an
organism, cell or tissue.
Proteome Metabolome
Genome Pharmacogenomics
Page 2 of 2
SLR-MK-422
Answer the following terms. 07
R scripting.
Comparative genomics.
Metabolome.
Pharmacoviglance.
Parasitic diseases.
Genome Mapping.
NGS.
Section-II
Attempt any four:
Q.2 Define clinical trial. Add a note on different stages. 14
Q.3 Write in detail various methods of NGS. 14
Q.4 Explain different types of host pathogen interactions. 14
Q.5 Answer any two of the following: 14
Add a note on Ensemble and Mapviewer.
Write a note Medical coding.
Explain the Human Genome Project.
Q.6 Answer any two of the following: 14
Pharmacogenomics.
Applications of metabolomics.
Systems biology.