M. Sc. Bioinformatics (Semester IV) (CBCS) Examination, 2017
CLINICAL BIOINFORMATICS
iI
Day Date: Friday, 21-04-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
N.B. Section-I, Question 1 is compulsory.
Attempt any four from Section-II
Figures to the right indicate full marks.
Answer to the Section-I and Section-II are to be written
in same answer Booklet only.
Section I
Q.1 Rewrite the sentence after choosing the correct answer from
the given alternatives.
07
1g) also called whole transciptome shotgun sequencing.
RNA Seq ChIp FAST A Transcriptomic
2 Peptic ulcers is caused by
E.coli Helicobacter pylori HIV Fungus
3 prepares a standardized bill for service given to
patient.
Payer Provider Occupational Client
4 fast quality control toolkit Illuminia sequencing data.
Pyroclenar FAST X PrinSek HTQC
Cancer is caused by
Hepatitis HIV
Human papilloma virus All of these
6 a genome browser for vertebrate genomes.
Google Ensembl PubMed NIH
Pharamcovigilance also called as
Safety Administration
Barrier Assessment
Definitions. 07
Cystic fibrosis
ADR
Mapviewer.
NGS library
SNPdb
BAM
Page 2 of 2
HTQC
Section II
Answer any four of the following.
Q.2 Explain in detail about types of Cancer. 14
Q.3 Explain quality control tool for Next generation sequencing data in details
and add a note on challenges for bioinformatics in NGS details.
14
Q.4 Genome data visualization using Ensemble and Map viewer. 14
Q.5 Answer any two from the following. 14
Explain Basic NGS chemistry in details.
Describe pathogen genomes.
Explain transcriptomics in details.
Q.6 Write short notes on (any two) 14
System Biology
Application of Pharamcovigilance
Challenges of HGP.