M.Sc. (Semester IV) (CBCS) Examination Nov/Dec-2018
Bioinformatics
CLINICAL BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: Part-1, Question 1 is compulsory.
Attempt any four questions from Part-II.
Figures to the right indicate full marks.
Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part I
Q.1 Rewrite the sentence after choosing the correct answer from the
given alternatives:
07
AB SOLID 3 System generates over gigabases per
turn.
30 20
15 50
locates the pair of genes on the chromosomes.
Map Viewer Linkage
Genetic Mapping All of these
disease is progressive loss of function of neurons including
death of neuron.
Alzeimer's Huntigton's
Parkinsons All of these
A wide variety of microarray analysis tool written in
C
Python R
jointly sponsored by American College of Surgeons
American Society.
NCDB MHDC
NHRD PHIBASE
is the intermediates and products of metabolism.
Metabolites Genomics
Proteomics None
to determine the amount to paid to provider.
Provider Payer
Patient Hospital
Definitions. 07
Linkage
COPD
Clinical Data Management
Adverse Drug Reaction
ChIP
Transcriptomics
System Dynamics
Page 2 of 2
SLR- VC-66
Part II
Answer any four of the following
Q.2 Explain Host Pathogen interaction in detail and add a note on host pathogen
interaction database.
14
Q.3 Give a brief account on pharmacogenomics and their application in details. 14
Q.4 Write in detail Next Generation Sequencing QC tools and add a note on basic
NGS Chemistry.
14
Q.5 Answer any two of the following. 14
Explain pathology informatics in details.
Explain De Novo genome sequencing
Explain goals and future challenges in Human Genome Project.
Q.6 Write short notes any two of the following. 14
International Classification disease
NGS Platforms
Ensembl Database