1. A rover on Mars crawls 100 meters south then 120 meters west, and 20 meters south again. It then moves 40 meters east before crawling 60 meters north. How far is the rover from its initial start point? .

170 meters

85 meters

100 meters

120 meters

2. The length of a rectangle is increased by 60%. By what percentage the width be decreased to
maintain the same area?

37% .

50%

120%

75%

3. A fabric needed to make 3 curtains, sells for $8.00 per yard, and can be purchased only by the full yard. If the length of fabric required for each curtain is 1.6 yards and all of the fabric purchased as a single length, what is the total cost of the fabric that needs to be purchased for the 3 curtains

$40.00

$38.40

$24.00

$16.00

4. Which of the following samples has the largest mass

1.42cm3 dIamond (densIty -2.84gm/cm

0.75 cm3 opal (density· 2.20 gm/cm3)

1.00 cm3 ivory (density-l.9gmJcm3)

0.65 cm3 coal (density-2.7gm/cm3)

5. What is the least positive integer that is not a factor of 25! and is not a prime number?

26

28

56

58

6. If which of the following inequalities must be true?





xy<y2

xy<x2

7. Consider following system of equations

2yz zx -5xy 2
yz -zx 1
yz -2zx 6xy 3.

What is the correct answer?

xyz=+6 and z=3

xyz=+6 and

xyz=-6 and z=3

xyz=6 and z=3

8. What is the perimeter, in meters, of a rectangular playground which is 24 meters wide and has same area as a rectangular playground 64 meters long and 48 meters wide

112

152

312

304

9. x3/1+x2 where a is a constant. What should be the value of a such that
for all

11/8

1

a>10/8

a>9/8

10. List K consists of numbers 5 and 10. Which of the following lists of numbers have the same range as the numbers in list K









11. Nuclear sizes are expressed in a unit called:

Fermi

Tesla

Newton

Angstrom

12. Sequence coverage in whole genome sequencing is dependent on:

Read length

Number of reads

Genome size

All of the above

13. Which of the following can be used to determine an alpha helical conformation of a protein
in a solution

UV absorbance spectroscopy

Circular dichroism

Ultracentrifugation

Electrophoresis

14. Consider the following pattern. Identify the missing number that should replace

<img src='./qimages/1677-14.jpg'><br><br>
4

8

9

12

15. Sound produced at a point is heard by a person after 5 second, while the same sound is heard by another person after 6 seconds. If the speed of sound is 300 mis, what could be the maximum and minimum distances between the two persons? 1.8 km, 0.15 km 2.2 km, 0.20 km 2.8 kIn, 0.25 kIn 3.3 km, 0.30 kIn

16.
A bag contains 4 white, 5 red and 6 blue balls. Three balls are drawn at random from the bag.


. The probability that all ofthem are red, is:
1/22
3/22
2/91
2/77


17.
In the xy-plane, line k is a line that does not pass through the origin. Which ofthe following statements individually provide(s) sufficient additional information to determine whether the slope ofthe line k is negative: The intercept ofline k is halfthe y-intercept ofline k The product ofthe x-intercept and the y-intercept ofline k is negative Line k passes through the points and where 0 Line k does n9t pass through the points and where 0

18.
The base adenine ofthe DNA of an organism is 21.3 of its total DNA composition; which of the following statement is correct for the base composition ofthe genome, given C is cytosine, G guanine and T thYmine? A=T=21.3%andG=C=28.7% A=C=28.7%andG=T=28.7% A=T=21.3%andG=C=21.3% A=T=28.7%andG=C=21.3%

19.
Phosphorus comes in different allotrophic forms in various colors. Which one is the standard state? White Admixture ofred and black Black Red

20.
The standard state of bromine is: solid liquid gas vapor

21.
Which one of the following statements is more correct about oxygen: It exists as 02 under normal state, not as liquid or oxygen atoms It can naturally exist as 03 (ozone) which is an allotrope ofoxygen The O2 form is energetically more stable than 03 All ofthe above

22.
A bike started from a point X is ridden with a constant velocity of60 km/hr. When will another bike ridden with a constant velocity of 90 km/hr started from the same point but after two hours, equId meet the first bike? 1 hrs. after the second bike was started 2 hrs. after the second bike was started 4 hrs. after the second bike was started 6 hrs. after the second bike was started

23.
Sensitive dependence of a system on initial conditions leads to large-scale effects elsewhere owing to small changes at one place. This phenomenon is called as: Butterfly effect



Time travel effect
Chaos theory
Boyle's law

24.
Bottle opener, see-saw, and stapler are the levers of, respectively,
class-I, class-II, and class-III
class-I, class-III, and class-II
class-II, class-I, and class-III
class-III, class-I, and class-II


25.
Which one of the following is correct with respect to the energy of electromagnetic


radiations?
Radio waves Ultraviolet Infrared X-ray
Radio waves Infrared Ultraviolet X-ray
Infrared Ultraviolet X-ray Radio waves
Infrared Ultraviolet Radio waves X-ray

PART-B
26. Which of the following technique is most suitable for detecting the presence of a gene
product
Dot blotting
Plaque bl,otting
Western blotting
Southern blotting

27.
A vector able to replicate into two different hosts is called Cloning vector Expression vector Secretion vector Shuttle vector:

28.
An amino acid that has a secondary amine and disrupts alpha-helix formation is Threonine Glycine Phenyl alanine Proline

29.
The following is a Y-linked phenomenon inheritance Occurrence of amelogenin loci



SRY genes
Genomic imprinting

30.
4-D is a structural analogue of Auxin Cytokinin Abscisic acid Brassinolide

31.
Which one of the following is true Epigenetics means alteration of both genotype and phenotype upon environmental


changes
Epigenetics does not involve a change in DNA sequence
Epigenetics involves mutation in DNA sequence
Gregor Mendel coined the term 'Epigenetics'

32.
Which ofthe fol1<?wing enzyme uses RNA as template to make DNA RNA polymerase Telomerase DNA polymerase III DNA polymerase alpha

33.
Reverse transcriptase enzyme is involved in Synthesis of complementary DNA from mRNA Synthesis of complementary mRNA from DNA To digest DNA-RNA complex To join to DNA fragments

34.
A technique that can be used to study protein location in cells MALDI-TOF Fluorescent microscopy NMR spectroscopy X-ray crystallography

35.
The oxidized form of glutathione is represented as GSH FAD NAD GSSG

36.
You engineered a bacteriophage that had the protein coat of T4 phage and the DNA of T2



phage. The composite bacteriophage was allowed to infect bacteria. What would be the composition of th.e new phages produced in the bacterial cells
New phages would have the protein coat ofT2 and the DNA ofT4
New phages would have the protein coat and DNA of T4
New phages would have the protein coat and DNA of T2

New phages would have a mixture ofthe DNA and proteins of both phages
37.
What is the chemical basis of gene imprinting
Phosphorylation ofDNA
Methylation of DNA
Oxidationof DNA
Glycosylation of DNA


38.
Which one of the following E. coli sigma subunit is required for transcription of heat inducible genes Sigma 70 Sigma 32


Sigma54
Sigma28

39. The substance that is the general biosynthetic precursor of sex hormones and hormones of
adrenal cortex is
Lecithin
Sphingomyelin

Phosphatidyl choline
Cholesterol

40. Anaplerotic reaction involves the conversion of pyruvate to
a-ketoglutarate
Acetyl-CoA

Oxaloacetate
Succinate

41. Molecular chaperones Are expressed only when cells are exposed to various stressful condition
Are present in nucleus and help in folding of DNA
.degrade proteins that have folded incorrectly
Help new proteins fold correctly and repair incorrectly folded proteins

42. Classification of bacteria into Gram positive and Gram negative categories is based upon: Shape Size
Staining
Flagella



r
43. With reference to the bacterial cell wall, which of the following statements is correct?
Gram +ve bacteria lack peptidoglycan
Gram -ve bacteria lack peptidoglycan

Both Gram +ve and Gram -ve bacteria possess peptidoglycan and the outer membrane Both Gram +ve and Gram-ve bacteria possess peptidoglycan but the Gram +ve bacteria lack outer membrane
44.
An example ofpeptide phytohormone
Jasmonic acid
Systemin
Salicylic acid
Oxylipin


45.
A hydrocarbon is said to be saturated if
It has one or nlore double bonds between carbon atoms
It contains more than one functional group
Each internal :carbon atom is covalently bonded to two hydrogen atoms
It should have at least one aromatic ring


46.
In enzyme kinetics, Kcat/Kmindicates
turnover number of an enzyme
ii) efficiency of an enzyme
iii) affinity of an enzyme



only
only
and only
only

47.
Rapid but non-antigen specific immune responses are produced by the Adaptive immune response Innate immune system Leukocytes Lymphatic system

48.
LYS2 is a selectable marker for Bacteriophase A E.coli


Yeast
Protozoa

49. The size of the viruses will be maximum in om

C)mm
cm"

50.
Which ofthe following are true with regard to interferons Activates B cells to make virus specific antibodies Are Th2 cytokines Are virus proteins that interfere with activation of cytotoxic T cells Inhibits virus replication by infected cells

51.
Which ofthe following disease is not an autoimmune disease Type-1 diabetes Celiac disease Alzheimer's disease Hashimoto's thyroidosis

52.
Mitosis produces a different number of cells than meiosis. Which ofthe following statements is true Mitosis produces two cells while meiosis produces four. Mitosis produces one-tenth the amount of cells as meiosis Meiosis produces two cells while mitosis produces four Meiosis produces one fifth the amount of cells as mitosis

53.
Down's syndrome results from The absence of one chromosome in position 21 The presence ofan extra chromosome in position 21 The absence of both the chromosomes in position 21 Crossing over on the chromosomes in position 21

54.
Which ofthe following is not the part of a virus Capsid Plastid Envelop Capsomere

55.
Alternative oxidase pathway is associated with Mitochondrial electron transport chain Chloroplastic electron transport chain Plasma membrane Nuclear membrane

56.
Antigen-presenting cells that activate helper T cells must express which one ofthe following on their surfaces IgE gamma interferon class I MHC antigens



class II MHC antigens
57.
Which of the following organisms would not undergo meiosis?

58.
The following phenomenon in plants influences their genome size determination: Ploidy Gene duplication Transposition Mutations and reversions

59.
Which of the following genetic elements in bacteria are acquired from an external donor Multiple CDS Shine-Dalgarno sequences Plasmids Core metabolic genes

60.
Which of the following can digest protein Lipase and trypsin Trypsin and pepsin Amylase and chymotrypsin Pepsin and lipase

61.
Restriction enzymes, enzymes which cut the DNA molecules, were discovered by Boyer and Cohen Jacob and Monad Watson and Crick Nathan, Arber and Smith

62.
A light receptor in certain bacteria resembles that found in the eyes of animals. What is the bacterial light receptor called Photochrome Chlorophyll Bacteriorhodopsin Rhodopsin

63.
Polynucleotide phosphorylase (PNPase) polymerizes following substrates when they are available in excess dNDPs dNTPs polydATPs NTPs

64.
An origin ofreplication is
A particular sequence in eukaryotic or prokaryotic DNA at which replication starts
A sequence to which single stranded binding proteins flock first to start replication
A sequence found in autonomously replicating plasmids
A DNA sequence responsible for making theta coils in a plasmid as a hallmark of



Bacteria
Fungi
Plant
Humans

11

replication
65.
Which of the following enzyme was firstly isolated in pure crystalline form Urease Zymase Oxygenase Hexokinase

66.
Which of the following amino acids absorb maximum UV light at 280nm Thr and Pro Trp and Tyr Phe and His Cys and Met

67.
Which one of the following is a M13 based vector pBR322 pT7blue pUC18 Cosmid

68.
The Maxam-Gilbert method of nucleotide sequencing is based on dideoxy nucleotide triphosphates chemical modifications of DNA PCR RT-PCR

69.
Which of the following is used for Global sequence alignment? Needleman and Wunsch algorithm Smith and Waterman algorithm Dot matrix algorithm ClusalW algorithm

70.
Unidirectional transmission of a nerve impulse through nerve fibre is due to the fact that Nerve fibre is insulated by a medullary sheath sodium pump starts operating only at the cyton and then continues into the nerve fibre Neurotransmitters are released by dendrites and not by axon endings Neurotransmitters are released by the axon endings and not by dendrites

71.
Which one ofthe following is a DNA binding protein



light chain proteins
C-Iectin type receptors
TNF Alpha
Nf-Kappa-B

72. The primary thermodynamic factor that favors the formation of a lipid bilayer in aqueous surrounding is Hydrogen bond Hydrophobic force Ionic interaction Covalent bonds
73. The enzyme which converts palmitic acid to palmitoleicacid is Hydrogenase Desaturase Hydrolase Catasase
74.
Gel electrophoresis is used
To size-separate DNA molecules
To digest DNA molecules based on their molecular weight
To ligate different DNA molecules
For amplification of DNA


75.
Raw honey is more wholesome than processed honey because:
It contains honey bees' probiotic bacteria and pollens
It contains color and aroma corresponding to the floral source of the nectar
It rarely contains harmful bacterial spores
All of the abov:e