Exam Details
Subject | imsc - ph.d - in biotechnology | |
Paper | ||
Exam / Course | ima/imsc | |
Department | ||
Organization | central university | |
Position | ||
Exam Date | 2017 | |
City, State | telangana, hyderabad |
Question Paper
1. Which of the following is correct according to boiling point of the compounds?
HF >HCl>H20 NH3
HF H20 NH3
H20> HF NH3
H20> HF NH3>HCl
2. 250 J of heat is required to increase the temperature of an ideal gas by 10 K at constant pressure. If the same gas is heated at constant volume, the amount of heat required to increase the temperature by 10K will be
126J
167 J
250J
333 J
3. The number of electrons in the outer orbital of semiconductors will be
Two
Four
Eight
Any of the above
4. Which of the following the equation represents the line with a y-intercept of 70 and a slope of l5?
Y=15x +70
X=70y +15
Y=70x +15
X=15y 70
5. What is the simple interest earned on Rs.50,000 invested for 6 months at a rate of per annum?
Rs.2,500
RS.750
Rs.1,250
Rs.625
6. The sides of a rectangle are in the ratio of 4:3 and its area is 108 cm^2. The perimeter of the rectangle in cm is
7. Which one of the following statements is correct?
Cellulose is a homopolymer of glucose
Insulin is a heteropolymer of glycine and tryptophan
Lactose consists of glucose and fructose
Maltose consists of galactose and glucose
8. Which one of the following breaks an ester bond?
Lipase
Hexokinase
Polymerase
Helicase
9. In the isolation of DNA, removal of protein and RNA is carried out by enzymes and respectively
Protease and cellulose
Lysozyme and ribonuclease
Protease and ribonuclease
Ribonuclease and chitinase
10. Highest electropositive element is
Cs
Fe
Au
Fr
11. MgO composed of
Covalent bond
Ionic bond
Metallic bond
Coordinated covalent bond
12. The number of moles of solute present in 600 ml of 0.05 M solution is
0.003
0.03
0.30
3.0
13. Absorption of dye solution on a blotting paper is due to
Viscosity of the dye
Diffusion of the dye
Capillary force
All the above
14. Area of a circle of radius 5 cm is .... Sqcm
3.14X5
3.14X5X5
3.14X5X5X5
14X 2X 5
15. Raju and Ramu own two pieces of adjacent lands. The area of both the lands together in square meters is three times the area of Ramu and is 750 square meters. What is the area ofRaju's land?
500 square meters
450 square meters
300 square meters
750 square meters
16. Which of the following molecules does not have a net dipole moment?
H20
NH3
BF3
BrF5
17. Atoms that have same number of protons but different number of neutrons are called
Isotope
Isobar
Isotone
Isomer
18. The orthocenter of the triangle formed by is
19. Which term of the AP: .... is
10th
12th
9th
8th
20. Which one of the following values will be positive?
sin
cosine
cos
tan
21. If circle represents guitarists, square represents singers and triangle represents dancers, the number of people who can sing and dance, but cannot play guitar are
<img src='./qimages/15975-21.jpg'>
Five
Three
Two
One
22. If a person standing on stationary boat throws a ball of 0.5 kg which travels with a speed of 10 what will be the speed of boat's movement after throwing the ball? Consider that the weight of the person and boat is 50 kg each and friction between the lake water and boat is insignificant.
(a)0.05 m/s
0.10 m/s
0.20 m/s
(d)0.50 m/s
23. A light of wavelength traveling in air is 480 nm which incidents on glass having refractive index of 1.5. The wavelength of light inside the glass will
320 nm
480 nm
560 nm
720 nm
24. The capacitance of a capacitor storing 0.5 C at 10 V is
20F
10F
0.1F
0.05F
25. Bronze is an alloy of
Copper and silver
Copper and mercury
Copper and tin
Copper and iron
26. Glyceraldehyde-3-phosphate is an isomer of
Fructose-6-phosphate
Dihydroxy acetone phosphate
Glucose-6-phosphate
Glycerol-3-phosphate
27. Codon bias and CpG islands are useful in eukaryotic genome to
Find the DNA binding domains
Identify gene function
Identify open reading frame
Identify repeats in DNA
28. The dye used to track the migration of proteins in the polyacrylamide gel electrophoresis
Xylene cyanol
B-mercaptoethanol
Bromophenol blue
Coomassie brilliant blue
29. Which technique can be used to detect the protein-protein interaction?
Co-immunoprecipation
Yeast-two hybrid system
FRET Microarray
All the above
30. 'Transversion' is a type of
Chromosomal aberration
Point mutation
Suppressor mutation
None of the above tryptophan?
31. Which of the following methods could be most readily employed to identify
Electrophoresis
Ultraviolet spectroscopy
Gel filtration chromatography
Analytical ultracentrifugation
32. Which vitamin is produced by the microorganisms present in normal microbiota?
Vitamin A
Vitamin C
Vitamin D
Vitamin K
33. In cation exchange chromatography, the solid support should be
Neutral
Zwitterion
Positively charged
Negatively charged
34. The term 'hyperglycemia' refers to
Increased blood sugar
Decreased blood sugar
Inhibits the process of gluconeogenesis
Stimulation of cellular glucose uptake by glucagon
35. Chemically'Agar' belongs to one of the following macromolecules
Nucleic acids
Proteins
Carbohydrates
Lipids
36. Which of the following set of amino acids consists of only apolar/hydrophobic side chains?
Ala, Leu, He, Phe
Ser, Gly, Pro, Leu
Gly, Lys, Asn, Arg
Ser, Glu, Asp, Thr
37. The chromatography in which the ligand is immobilized to the column matrix is
Gel Filtration
Affinity
Ion exchange
Hydrophobic
38. The compound which cannot be metabolized to pyruvate is
Alanine
Cysteine
Serine
Phenylalanine
39. STRING is a database of
Protein sequences
Protein structures
Protein-Protein interaction networks
DNA sequences
40. The immunoglobulin that results in the histamine release is
IgG
IgM
IgE
IgD
41. The slope Km/Vmax indicate
Competitive inhibition
Un-Competitive inhibition
Non-Competitive inhibition
Allosteric Inhibition
42. Gene bank is a nucleic acid sequence database which is maintained by
DNA database Japan
National Centre for Biotechnology Information (NCBI)
European Molecular Biology Laboratory
Sanger Institute
43. Characteristic feature of allosteric protein is
Kcat is very high
Cooperativity
Aggregation
Helix-coil transition
44. has very restricted conformational freedom
Pro
Gly
His
Trp
45. Hoogstein hydrogen bonding is present in
Z-DNA
RNA
Triplex DNA
B-DNA
46. If a heterogenous offspring is crossed with homogenous recessive parent, such activity is called
Back cross
Reciprocal cross
Test cross
Dihybrid cross
47. Aneuploidy refers to
2n
2n+l
4n
4n+1
48. Following is associated with breast cancer
BRCAI
BRCA2
Both
Neither
49. SOS response involves
Thymidine dimer formation
DNA strand breaks
Lex A cleavage
All the above
50. Hydrogen bond is formed between
An uncharged hydrogen atom with an uncharged atom
A partially positively charged hydrogen atom with a partially negatively charged electronegative atom
A partially positively charged hydrogen atom with an uncharged electronegative atom
An uncharged hydrogen atom with a partially negatively charged electronegative atom
51. The severely affected people who possesses most common form having more than 1000 repeats of the CTG triplet is
Myotonic dystrophy
Fragile X syndrome
Retinoblastoma
None of the above
52. Protein surface is predominantly comprises of amino acid residues
Polar
Apolar/hydrophobic
Neutral
Charged
53. In an ideal a-helix every carbonyl oxygen of an amino acid residue "i" is hydrogen bonded to an amide hydrogen of amino acid residue" "
i+l
i+2
i+3
i+4
54. Which of the following statements concerning proteins is CORRECT?
Alpha helices are stabilized by hydrogen bonding between the carbonyl oxygen and the amide hydrogen of amino acids.
Proteins are the only molecules that can catalyze reactions in the cell.
The peptide bond is formed through a hydrolysis reaction.
Disulfide bonds are formed from ionic interactions between charged amino acids.
55. Which statement about mitochondrial genomes is FALSE?
They use a genetic code different from the standard eukaryotic genetic code.
Their genes do NOT have introns.
They probably arose as a result of a symbiotic event with formerly free living organisms.
They contain genes necessary for all mitochondrial functions.
56. Which of the following has the highest percentage of modified bases?
hnRNA
(b)mRNA
rRNA
tRNA
57. Which of the following enzymes in the anabolic pathway given below is most likely to catalyze the rate limiting step in the biosynthesis of A6?
EE L A. j E.,
E1
E2
E3
Es
58. Which one is a common compound shared by the TCA cycle and the urea cycle?
a-keto glutarate
Argino succinic acid
Fumarate
Aspartic acid
59. Which of the following statements best describe an allosteric binding site?
It is a binding site containing amino acids with aliphatic side chains.
It is a binding site that can accept a wide variety of differently shaped molecules.
It is a binding site, which is separate from the active site, and affects the activity of an enzyme when it is occupied by a ligand.
It is a description of an active site which has undergone an induced fit.
60. BCG vaccine is used for
TB
Cholera
Plague
Influenza
61. Chemical mediated introduction of DNA into a bacterial cell termed as
Transformation
Transcription
Transduction
Conjugation
62. The antibiotic that does not bind to the ribosome is
Streptomycin
Tetracycline
Erythromycin
Penicillin
63. Monoclonal antibodies are against
Single antigen
Single epitope
Single paratope
Single antibody
64. The cell wall ofthe following is not rigid in
Fungus
Archaea
Protozoa
Bacteria
65. The amino acid that shows characteristic absorbance at 280 nm is
Methionine
Lysine
Valine
Tryptophan
66. The codon UAA codes for
Methionine
Threonine
Tryptophan
Termination
67. 'Toxemia'means
A disease caused by toxins
Circulation of toxins in the blood
Secretion of toxins by microbes
Inactivation of toxins
68. Collagen has
Single helical structure
Double helical structure
Triple helical structure
No defined structure and is disordered
69. Rapid but non-antigen specific immune responses are produced by the
Adaptive immune response
Innate immune system
Leukocytes
Lymphatic system
70. Deficiency of thymus results in increased infections in humans, such a condition is called
Thymectomy
Graves disease
DiGeorges syndrome
All the above
71. In Krebs cycle two moles of glucose produces
1 mole of ATP
2 moles of ATP
4 moles of ATP
8 moles of ATP
72. A 'bioreactor' is a
Analyzer
Fermenter
Radiator
Coolater
73. Prokaryotic translation elongation factor G its activity
(a)GTP
(b)ATP
(c)CTP
(d)UTP
74. Viroids consists of
Only proteins
Only envelops
Only capsids
Only nucleic acids
75. During the bacterial growth, the primary metabolites will be produced during
Lag phase
Log phase
Stationary phase
Decline phase
HF >HCl>H20 NH3
HF H20 NH3
H20> HF NH3
H20> HF NH3>HCl
2. 250 J of heat is required to increase the temperature of an ideal gas by 10 K at constant pressure. If the same gas is heated at constant volume, the amount of heat required to increase the temperature by 10K will be
126J
167 J
250J
333 J
3. The number of electrons in the outer orbital of semiconductors will be
Two
Four
Eight
Any of the above
4. Which of the following the equation represents the line with a y-intercept of 70 and a slope of l5?
Y=15x +70
X=70y +15
Y=70x +15
X=15y 70
5. What is the simple interest earned on Rs.50,000 invested for 6 months at a rate of per annum?
Rs.2,500
RS.750
Rs.1,250
Rs.625
6. The sides of a rectangle are in the ratio of 4:3 and its area is 108 cm^2. The perimeter of the rectangle in cm is
7. Which one of the following statements is correct?
Cellulose is a homopolymer of glucose
Insulin is a heteropolymer of glycine and tryptophan
Lactose consists of glucose and fructose
Maltose consists of galactose and glucose
8. Which one of the following breaks an ester bond?
Lipase
Hexokinase
Polymerase
Helicase
9. In the isolation of DNA, removal of protein and RNA is carried out by enzymes and respectively
Protease and cellulose
Lysozyme and ribonuclease
Protease and ribonuclease
Ribonuclease and chitinase
10. Highest electropositive element is
Cs
Fe
Au
Fr
11. MgO composed of
Covalent bond
Ionic bond
Metallic bond
Coordinated covalent bond
12. The number of moles of solute present in 600 ml of 0.05 M solution is
0.003
0.03
0.30
3.0
13. Absorption of dye solution on a blotting paper is due to
Viscosity of the dye
Diffusion of the dye
Capillary force
All the above
14. Area of a circle of radius 5 cm is .... Sqcm
3.14X5
3.14X5X5
3.14X5X5X5
14X 2X 5
15. Raju and Ramu own two pieces of adjacent lands. The area of both the lands together in square meters is three times the area of Ramu and is 750 square meters. What is the area ofRaju's land?
500 square meters
450 square meters
300 square meters
750 square meters
16. Which of the following molecules does not have a net dipole moment?
H20
NH3
BF3
BrF5
17. Atoms that have same number of protons but different number of neutrons are called
Isotope
Isobar
Isotone
Isomer
18. The orthocenter of the triangle formed by is
19. Which term of the AP: .... is
10th
12th
9th
8th
20. Which one of the following values will be positive?
sin
cosine
cos
tan
21. If circle represents guitarists, square represents singers and triangle represents dancers, the number of people who can sing and dance, but cannot play guitar are
<img src='./qimages/15975-21.jpg'>
Five
Three
Two
One
22. If a person standing on stationary boat throws a ball of 0.5 kg which travels with a speed of 10 what will be the speed of boat's movement after throwing the ball? Consider that the weight of the person and boat is 50 kg each and friction between the lake water and boat is insignificant.
(a)0.05 m/s
0.10 m/s
0.20 m/s
(d)0.50 m/s
23. A light of wavelength traveling in air is 480 nm which incidents on glass having refractive index of 1.5. The wavelength of light inside the glass will
320 nm
480 nm
560 nm
720 nm
24. The capacitance of a capacitor storing 0.5 C at 10 V is
20F
10F
0.1F
0.05F
25. Bronze is an alloy of
Copper and silver
Copper and mercury
Copper and tin
Copper and iron
26. Glyceraldehyde-3-phosphate is an isomer of
Fructose-6-phosphate
Dihydroxy acetone phosphate
Glucose-6-phosphate
Glycerol-3-phosphate
27. Codon bias and CpG islands are useful in eukaryotic genome to
Find the DNA binding domains
Identify gene function
Identify open reading frame
Identify repeats in DNA
28. The dye used to track the migration of proteins in the polyacrylamide gel electrophoresis
Xylene cyanol
B-mercaptoethanol
Bromophenol blue
Coomassie brilliant blue
29. Which technique can be used to detect the protein-protein interaction?
Co-immunoprecipation
Yeast-two hybrid system
FRET Microarray
All the above
30. 'Transversion' is a type of
Chromosomal aberration
Point mutation
Suppressor mutation
None of the above tryptophan?
31. Which of the following methods could be most readily employed to identify
Electrophoresis
Ultraviolet spectroscopy
Gel filtration chromatography
Analytical ultracentrifugation
32. Which vitamin is produced by the microorganisms present in normal microbiota?
Vitamin A
Vitamin C
Vitamin D
Vitamin K
33. In cation exchange chromatography, the solid support should be
Neutral
Zwitterion
Positively charged
Negatively charged
34. The term 'hyperglycemia' refers to
Increased blood sugar
Decreased blood sugar
Inhibits the process of gluconeogenesis
Stimulation of cellular glucose uptake by glucagon
35. Chemically'Agar' belongs to one of the following macromolecules
Nucleic acids
Proteins
Carbohydrates
Lipids
36. Which of the following set of amino acids consists of only apolar/hydrophobic side chains?
Ala, Leu, He, Phe
Ser, Gly, Pro, Leu
Gly, Lys, Asn, Arg
Ser, Glu, Asp, Thr
37. The chromatography in which the ligand is immobilized to the column matrix is
Gel Filtration
Affinity
Ion exchange
Hydrophobic
38. The compound which cannot be metabolized to pyruvate is
Alanine
Cysteine
Serine
Phenylalanine
39. STRING is a database of
Protein sequences
Protein structures
Protein-Protein interaction networks
DNA sequences
40. The immunoglobulin that results in the histamine release is
IgG
IgM
IgE
IgD
41. The slope Km/Vmax indicate
Competitive inhibition
Un-Competitive inhibition
Non-Competitive inhibition
Allosteric Inhibition
42. Gene bank is a nucleic acid sequence database which is maintained by
DNA database Japan
National Centre for Biotechnology Information (NCBI)
European Molecular Biology Laboratory
Sanger Institute
43. Characteristic feature of allosteric protein is
Kcat is very high
Cooperativity
Aggregation
Helix-coil transition
44. has very restricted conformational freedom
Pro
Gly
His
Trp
45. Hoogstein hydrogen bonding is present in
Z-DNA
RNA
Triplex DNA
B-DNA
46. If a heterogenous offspring is crossed with homogenous recessive parent, such activity is called
Back cross
Reciprocal cross
Test cross
Dihybrid cross
47. Aneuploidy refers to
2n
2n+l
4n
4n+1
48. Following is associated with breast cancer
BRCAI
BRCA2
Both
Neither
49. SOS response involves
Thymidine dimer formation
DNA strand breaks
Lex A cleavage
All the above
50. Hydrogen bond is formed between
An uncharged hydrogen atom with an uncharged atom
A partially positively charged hydrogen atom with a partially negatively charged electronegative atom
A partially positively charged hydrogen atom with an uncharged electronegative atom
An uncharged hydrogen atom with a partially negatively charged electronegative atom
51. The severely affected people who possesses most common form having more than 1000 repeats of the CTG triplet is
Myotonic dystrophy
Fragile X syndrome
Retinoblastoma
None of the above
52. Protein surface is predominantly comprises of amino acid residues
Polar
Apolar/hydrophobic
Neutral
Charged
53. In an ideal a-helix every carbonyl oxygen of an amino acid residue "i" is hydrogen bonded to an amide hydrogen of amino acid residue" "
i+l
i+2
i+3
i+4
54. Which of the following statements concerning proteins is CORRECT?
Alpha helices are stabilized by hydrogen bonding between the carbonyl oxygen and the amide hydrogen of amino acids.
Proteins are the only molecules that can catalyze reactions in the cell.
The peptide bond is formed through a hydrolysis reaction.
Disulfide bonds are formed from ionic interactions between charged amino acids.
55. Which statement about mitochondrial genomes is FALSE?
They use a genetic code different from the standard eukaryotic genetic code.
Their genes do NOT have introns.
They probably arose as a result of a symbiotic event with formerly free living organisms.
They contain genes necessary for all mitochondrial functions.
56. Which of the following has the highest percentage of modified bases?
hnRNA
(b)mRNA
rRNA
tRNA
57. Which of the following enzymes in the anabolic pathway given below is most likely to catalyze the rate limiting step in the biosynthesis of A6?
EE L A. j E.,
E1
E2
E3
Es
58. Which one is a common compound shared by the TCA cycle and the urea cycle?
a-keto glutarate
Argino succinic acid
Fumarate
Aspartic acid
59. Which of the following statements best describe an allosteric binding site?
It is a binding site containing amino acids with aliphatic side chains.
It is a binding site that can accept a wide variety of differently shaped molecules.
It is a binding site, which is separate from the active site, and affects the activity of an enzyme when it is occupied by a ligand.
It is a description of an active site which has undergone an induced fit.
60. BCG vaccine is used for
TB
Cholera
Plague
Influenza
61. Chemical mediated introduction of DNA into a bacterial cell termed as
Transformation
Transcription
Transduction
Conjugation
62. The antibiotic that does not bind to the ribosome is
Streptomycin
Tetracycline
Erythromycin
Penicillin
63. Monoclonal antibodies are against
Single antigen
Single epitope
Single paratope
Single antibody
64. The cell wall ofthe following is not rigid in
Fungus
Archaea
Protozoa
Bacteria
65. The amino acid that shows characteristic absorbance at 280 nm is
Methionine
Lysine
Valine
Tryptophan
66. The codon UAA codes for
Methionine
Threonine
Tryptophan
Termination
67. 'Toxemia'means
A disease caused by toxins
Circulation of toxins in the blood
Secretion of toxins by microbes
Inactivation of toxins
68. Collagen has
Single helical structure
Double helical structure
Triple helical structure
No defined structure and is disordered
69. Rapid but non-antigen specific immune responses are produced by the
Adaptive immune response
Innate immune system
Leukocytes
Lymphatic system
70. Deficiency of thymus results in increased infections in humans, such a condition is called
Thymectomy
Graves disease
DiGeorges syndrome
All the above
71. In Krebs cycle two moles of glucose produces
1 mole of ATP
2 moles of ATP
4 moles of ATP
8 moles of ATP
72. A 'bioreactor' is a
Analyzer
Fermenter
Radiator
Coolater
73. Prokaryotic translation elongation factor G its activity
(a)GTP
(b)ATP
(c)CTP
(d)UTP
74. Viroids consists of
Only proteins
Only envelops
Only capsids
Only nucleic acids
75. During the bacterial growth, the primary metabolites will be produced during
Lag phase
Log phase
Stationary phase
Decline phase
Other Question Papers
Subjects
- ima in hindi
- ima in humanities
- ima social sciences
- imsc - ph.d - in biotechnology
- imsc earth sciences
- imsc in health psychology
- imsc in nursing science
- imsc in optometry & vision sciences
- imsc in sciences