1. What is the essential requirement for the operation of a step down transformer?

A laminated iron core

A non-conducting core

A magnetic interaction between the primary and secondary coils

An electric connection among the primary and secondary coils

2. A fast moving space probe passes close to a planet. How does the gravitational environment of the planet influences the probe/or otherwise?

Its speed changes but direction remains same

Both the speed and direction of the probe change

The direction changes while speed remains constant

The gravitational environment of the planet will have no effect on the probe

3. What is the total number of sigma bonds found in the following compound?


11

5

10

13

4. If the enthalpy change for a reaction is zero, delta Go is equal to

delta H0

ln Keq

T deltaS0

-TdeltaS0

5. The identity of an element is determined by...

the number of its protons

the number of its neutrons

density of the element

its atomic mass

6. Osteoporosis is the disease of which organ?

A) Bones

B) Muscles

C) Eyes

D) Kidneys

7. One of the following is not a model organism used in biological studies:

A) Drosophila melanogaster

B) Neurospora crassa

C) Bostaurus

D) Escherichia coli

8. One of the following viruses is strongly associated with the development of cancer:

A) HIV

B) Visna-Maedi virus

C) HINI

D) Rabies virus

9. The following is a system of communication and response among organisms based on their population density:

A) Quorum quenching

B) Quorum sensing

C) Quorum glow

D) Biofilm formation

10. Which genetic element is very important in rapid acquisition and transfer ofdrug resistance among bacteria:

A) Integron

B) IS element

C) Plasmid

D) Prophage


11. The x-component of the resultant of several vectors

Is equal to the sum of the x-components of the vectors

May be smaller than the sum of the magnitude

May be equal to the sum of the magnitudes of the vectors

All the above.

12. While walking on the ice, one should take small steps to avoid slipping. This is because smaller steps ensure

Larger normal force

Larger friction

Smaller friction

Smaller normal force

13. A neutron exerts a force on a proton which is

Gravitational

Electromagnetic

Weak

All the above

14. A coin placed on rotating turntable just slips if it is placed at a distance of 4cm from the centre. If the angular velocity of the turntable is doubled, it will just slip at a distance of

2cm

4cm

8cm

1cm

15. The following is not a mechanism of genetic recombination:

Conjugation

Transduction

Gene conversion

Sumoylation

16. Which among the following is not a product of bacterial fermentation

Carbon dioxide

Hydrogen

Oxygen

Methane

17. Metabolic pathways like tricarboxylic acid cycle has

Both catabolic and anabolic functions

Catabolic functions only

Anabolic functions only

None of the above functions

18. An oxidation-reduction reaction involves

Internal rearrangment of a molecule

Cleavage of a large molecule into smaller molecule

Transfer of electrons from one molecule to another

Combining two small molecules to create one larger one

19. If you remove all of the functional groups from an organic molecule so that it has only carbon and hydrogen atoms, the molecule becomes a __molecule

Carbohydrate

Carbonyl

Carboxyl

Hydrocarbon

20. Which of the following quantities remain constantin a planetary motion (consider elliptical orbits) as seen from the sun

Kinetic energy

Angular speed

Angular momentum

Speed

21. A hydrocarbon is said to be saturated if

One end ofthe molecule is hydrophilic while the other end is hydrophobic

It has one or more double bonds between carbon atoms

It contains more than one functional group

Each internal carbon atom is covalently bonded to two hydrogen atoms

22. Molecular empirical formula for carbohydrates is

(CHO)2

(CH20)n

2(CHO)n

(C2HO)n


23. The substance that is the general biosynthetic precursor of sex hormones and hormones of adrenal cortex is

Lecithin

Sphingomyelin

Phosphatidyl choline

Cholesterol

24. An amino acid that has a secondary amine and disrupts alpha-helix formation is

Threonine

Glycine

Phenyl alanine

Proline

25. The Maxam-Gilbert method of nucleotide sequencing is based on

dideoxy nucleotide triphosphates

chemical modifications of DNA

PCR

RT-PCR


26. Which of the following is not a mechanism whereby B cells or antibodies contribute to immunity?

Presentation of antigen to T cells

Direct cell killing

Opsonization

Complement activation

27. T cells mature in the

Thyroid gland

Spleen

Lymph nodes

None of the above


28. Which of the following is a prime example of a ribonucleoprotein enzyme, the catalytic activity of which (under nonphysiological conditions), resides solely in its RNA component?

A) Polynucleotide phosphorylase

B) Reverse transcriptase

C) RNase P

D) Bacterial RNA polymerase

29. A light receptor in certain bacteria resembles that found in the eyes of animals. What is the bacterial light receptor called?

A) Photochrome

B) Chlorophyll

C) Bacteriorhodopsin

D) Rhodopsin

30. What is the chemical basis of gene imprinting?

A) Phosphorylation of DNA

B) Methylation of DNA

C) Oxidation of DNA

D) Glycosylation of DNA

31. Which of the following types of genes are not known in any mitochondrial geneome?

tRNA genes

Respiratory chain genes

Glycolytic genes

rRNA genes

32. When proteins are hydrolyzed to amino acids and then deaminated, the carbon skeleton is fed into

Glycolysis pathway

Pentose phosphate pathway

Tricarboxylic acid cycle

Calvin pathway

33. The Ames test is used to determine if a chemical

increases the rate at which a bacterial cell divide

decreases the number of cells in a culture

induces mutations in a cell's DNA

decreases the ability of a cell to photosynthesize

34. The precursor for fatty acid biosynthesis is

Histidine

Phenylalanine

Malonyl CoA

Acetyl CoA

35. Which among the following rRNA genes are compared for bacterial phylogeny

18S

16S

28S

5.8S

36. "Sucrose density gradient" is a technique used

In Purifying macromolecules and nucleic acids

To isolate the nucleic acids

To determine the molecular weight of virus particles

To detect the virus particles in an infected plant

37. Using viral nucleic acid (specifically the RNA) as a template, the c-DNA is synthesized by using this enzyme

T4 DNA ligase

Exo III nuclease

Reverse transcriptase

RNase H

38. Which of the following inhibits transcription

Rifampicin

Ampicillin

Chloramphenicol

Kanamycin

39. Following is a technique used for RNA transfer from gel to positively charged membrane

Southern

Northern

Western

Transformation

40. The living organism whose genome was the first to be completely sequenced

piex174

H.influenzae

Yeast

E.coli

41. A principal difference between prokaryotic and eukaryotic DNA replication is

Completely different proteins/enzymes in eukaryotes

Multiple origins in eukaryotes

No requirement for topoisomerase activity in prokaryotes

The absence of a nucleus in prokaryotes

42. Most of the important functional groups on biological molecules

Contain oxygen and/or nitrogen and are acidic

Contain oxygen and an amine

Contain nitrogen and a phosphate

Contain oxygen and/or nitrogen and are polar

43. Why is cellulose so difficult for most animals to digest?

They don't have proper enzymes to break the bonds between subunits

Cellulose is made up of chitin, which is indigestible

The bonds holding cellulose subunits together are extremely strong, stronger than any other macromolecules

None of the above

44. Triacylglycerol contains fatty acids and

Glucose

Glycogen

Glycerol

Guanine

45. Which of the following is not a lipid?

Chitin

Terpenes

Steroids

Prostaglandins

46. Each protein has a particular 3D structure which is decided by its

Secondary structure

Tertiary structure

Primary structure

Quaternary structure

47. The immunoglobulin that results in histamine release is

IgG

IgM

IgE

IgD

48. Which of these are involved in innate defense mechanisms?

Neutrophils

Macrophages

Lymphocytes

All of the above

49. Acquired immunity is found in

Invertebrates

Vertebrates

Some invertebrates

Both vertebrates and invertebrates

50. ELISA, used to detect antigens or antibodies, utilizes those enzymes that

have a high turnover rate

yield a stable colored product

are stable on conjugation to proteins

all of the above

51. The tuberculin skin test is an example of

Type IV delayed hypersensitivity

Allergy reaction

Serum sickness

Precipitation reaction

52. The macrophage-rich mass found at the site of injection of an adjuvant is called

myeloma

granuloma

adjuvant activated lymphoma

none of the above


53. The class of immunoglobulins that can get transported across epithelial cells is

IgG

IgE

IgA

IgM

54. MHC I genes that encode for membrane bound glycoprotein's are found in

All nucleated cells

B cells, macrophages, dendritic cells

Only Band T cells

Tumor cells

55. Joining chain chain) is found in

IgM

IgA

IgM and IgA

IgE

56. does not include

OH-

H2O2

NO

HZPO4

57. Factor VIII produced as a therapeutic using mammalian cell cultures is used to cure

Anaemia

Thrombosis

Haemophilia

Leukemia

58. Frankia species participate in symbiotic association with

Parasponia

Casuarina

Azolla

Cycas

59. A child disturbs a wasp nest, is stung repeatedly, and goes into shock within minutes, manifesting respiratory failure and vascular collapse. This is MOST likely to be due to

Systemic anaphylaxis

Serum Sickness

Arthus reaction

Cytotoxic hypersensitivity

60. Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

IgE

gamma interferon

class I MHC antigens

class II MHC antigens

61. Signals required for T cell activation

Peptide-MHC complex

Co-stimulation

Cytokines and other effectors molecules etc.

All

62. Rapid but non-antigen specific immune responses are produced by the

Adaptive immune response

Innate immune system

Leukocytes

Lymphatic system

63. Which of the following are true with regard to interferons

Activates B cells to make virus specific antibodies

Are Th2 cytokines

Are virus proteins that interfere with activation of cytotoxic T cells

Inhibits virus replication by infected cells

64. Cells that release histamine and other vasoactive substances in response to allergens are

Neutrophils

Macrophages

NK cells

Mast cells

65. Which of the following disease is not an autoimmune disease

rheumatoid arthritis

lupus erythematosus

bovine spongiform encephalitis

grave's disease

66. One of the following is not a bacterial pathogen

Bacillus anthracis

Leishmania tropica

Salmonella typhi

Streptococcus aureus

67. One of the following is very strong evolutionary force that influences bacterial taxonomy

Horizontal gene transfer

Selection for virulence alleles

Antigenic variation

Patho-adaptation

68. The bacterium that uses special secretary apparatus

Agrobacterium tumifaciens

Bacillus cereus

Lactobacillus delbrueckii

Lactococcus lactis

69. The following virus is a very strong cause of cervical cancer in humans

Human papilloma virus

JC-Polyoma virus

H INl virus

SARS corona virus

70. The following is an important viral enzyme that is the target ofpopular anti-influenza drugs

Neuraminidase

HIV protease

RNA polymerase

Topoisomerase

71. The following culture medium is commonly used to culture laboratory strains of E.coli

Luria-Bertani medium

Mannitol salt agar

Blood agar

Brain-heart infusion medium

72. The following is not a chronic disease/infection

Tuberculosis

Typhoid

Bacterial meningitis

Crohn's disease


73. The reason for the emergence of multiple drug resistant strains of pathogens in India is

Under dosage due to negligence or illiteracy

Uncontrolled over the counter sale of drugs

Lack of a proper antibiotic policy

All of the above

74. The following parasitic infection/disease can affect the brain seriously

Malaria

Amoebic dysentery

Elephantiasis

Kala-azar

75. The following part of the chromosomes is related to ageing in humans

Telomeres

Chromatin

Prophages

Homopolymeric tracts