THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LM 351] MAY 2018 Sub. Code: 2912
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH IV PHARMACOLOGY
PAPER III BIOLOGICAL STANDARDISATION AND PHARMACOLOGICAL
SCREENING METHODS
Q.P. Code 262912
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Different blood collection techniques employed in laboratory animals.
Various techniques of Euthanasia.
2. Discuss the various methods employed in the screening of anti-hypertensive
agents.
II. Write notes on: (10 x 6 60)
1. Despair swim test.
2. Brewer's yeast-induced pyrexia.
3. Bio-assay of Oxytocin.
4. Y maze test.
5. Two methods for the screening of anti-arrhythmic drugs.
6. Student's test.
7. Acute toxicity studies.
8. Different human cell lines used in screening techniques.
9. Charcoal meal test.
10. Any two methods for the screening of Anti-hyperlipidemic activity.